CarboDB Capsular polysaccharide 500 antigen 1376

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Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide 500 antigen

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Cryptosporidium parvum

[edit] Basic Structure

CPS-500 is a chloroform-extractable glycolipid

[edit] Proposed functions

CPS-500 is a candidate target antigen for active or passive immunization against cryptosporidiosis

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 18.44

[edit] Antibody type and class

IgG3

[edit] Assay System

ELISA, immunoblotting

[edit] Cross-reactivity

N/A

[edit] Proposed epitopes

the neutralization-sensitive epitope recognized by MAb 18.44 is dependent on terminal β-D-mannopyranosyl residues

[edit] Proposed Utility

MAb 18.44 neutralizes the infectivity of both sporozoites and merozoites and to significantly reduce C. parvum infection in oocyst-challenged mice when coadministered with other neutralizing Mab

[edit] Weblink

PubMed

[edit] External Links

• Link to CarboDB database