Rv0291
From DrugPedia: A Wikipedia for Drug discovery
(New page: {{immunebox | Name =<b> membrane-anchored mycosin </b> |image= | width=250 |image2= |Swiss Prot = O53695 | Genbank = 886615 | PDB = 3FIG, 1SR9 | DrugBank ...) |
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|Swiss Prot = O53695 | |Swiss Prot = O53695 | ||
| Genbank = 886615 | | Genbank = 886615 | ||
| - | | PDB = | + | | PDB = |
| DrugBank = | | DrugBank = | ||
| chemical_formula = C16H9F3N2O2 [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=886615&loc=ec_rcs] | | chemical_formula = C16H9F3N2O2 [http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=886615&loc=ec_rcs] | ||
Current revision
| Rv0291
| |
| Name | |
| membrane-anchored mycosin | |
| Identifiers | |
| Swiss Prot | |
| Genbank | |
| PDB | ? |
| Chemical data | |
| Formula | C16H9F3N2O2 [1] |
| Mol. wt. | 46128 Da |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Solubility | ? |
| Isoelectric-Point | 5.1 |
Contents |
[edit] General
PROBABLE MEMBRANE-ANCHORED MYCOSIN MYCP3 (SERINE PROTEASE) (SUBTILISIN-LIKE PROTEASE) (SUBTILASE-LIKE) (MYCOSIN-3) THOUGHT TO HAVE PROTEOLYTIC ACTIVITY.
Essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003) mutants available at TARGET website
[edit] Protein Sequence
>Rv0291, TB.seq 354496:355878 MW:46128 MIRAAFACLAATVVVAGWWTPPAWAIGPPVVDAAAQPPSGDPGPVAPMEQRGACSVSGVIPGTDPGVPTPSQTMLNLPAA WQFSRGEGQLVAIIDTGVQPGPRLPNVDAGGDFVESTDGLTDCDGHGTLVAGIVAGQPGNDGFSGVAPAARLLSIRAMST KFSPRTSGGDPQLAQATLDVAVLAGAIVHAADLGAKVINVSTITCLPADRMVDQAALGAAIRYAAVDKDAVIVAAAGNTG ASGSVSASCDSNPLTDLSRPDDPRNWAGVTSVSIPSWWQPYVLSVASLTSAGQPSKFSMPGPWVGIAAPGENIASVSNSG DGALANGLPDAHQKLVALSGTSYAAGYVSGVAALVRSRYPGLNATEVVRRLTATAHRGARESSNIVGAGNLDAVAALTWQ LPAEPGGGAAPAKPVADPPVPAPKDTTPRNVAFAGAAALSVLVGLTAATVAIARRRREPTE
[edit] Human Homologue Blast Result
| subject ids | % identity | % positives | alignment length | evalue |
| sp|Q14703.1 | 23 | 37 | 352 | 6e-04 |
| sp|P29144.4 | 26 | 38 | 213 | 0.006 |
| sp|Q8NBP7.2 | 31 | 48 | 87 | 0.43 |
| sp|Q9Y6V0.3 | 35 | 42 | 77 | 1.5 |
| sp|Q8N1I0.2 | 24 | 47 | 65 | 1.6 |
[edit] Alergen Protein
Link to Algpred
ALLERGEN (By IgE method)
[edit] Bacterial Toxin Prediction
Link to btxpred
No Hit Fountd by btxpred server.
[edit] Subcellular Location
Link to TBpred
Integral Membrane
[edit] Antigens
No Hit Found in AntigenDB
No. Hit Found in IEDB
[edit] B cell Epitopes
[edit] BCEpred Analysis
Link to Bcepred
Result Predicited by [2]
[edit] ABCpred Analysis
Link to ABCpred
Result Predicited by [3]
[edit] IEDB Analysis
Link to IEDB
Result Predicited by [4]
[edit] MHC Class-I Binder
[edit] nHLAPred Analysis
Link to nHLApred
Result Predicited by [5]
[edit] IEDB Analysis
Link to IEDB
Result Predicted by [6]
[edit] MHC Class-II Binder
[edit] Propred Analysis
Link to Propred
Result Predicted by [7]
[edit] NetMHC-II Analysis
Link to NetMHC-II
Result Predicted by [8]
[edit] External Links
- Database of Mycobacterium tuberculosis genome sequences and related information.
