Rv3634c
From DrugPedia: A Wikipedia for Drug discovery
| Line 1: | Line 1: | ||
{{immunebox | {{immunebox | ||
| - | | Name =<b> | + | | Name =<b> galE1 </b> |
|image= | |image= | ||
| width=250 | | width=250 | ||
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| PDB = | | PDB = | ||
| DrugBank = | | DrugBank = | ||
| - | | chemical_formula = | + | | chemical_formula = C10H12ClNO2 [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pccompound&term=885765] |
| molecular_weight = 33550 Da | | molecular_weight = 33550 Da | ||
| solubility = | | solubility = | ||
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=Subcellular Location= | =Subcellular Location= | ||
Link to [http://www.imtech.res.in/raghava/tbpred/ TBpred]<br> | Link to [http://www.imtech.res.in/raghava/tbpred/ TBpred]<br> | ||
| - | + | Cytoplasmic | |
=Antigens= | =Antigens= | ||
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Link to [http://www.imtech.res.in/raghava/bcepred/bcepred_submission.html Bcepred] | Link to [http://www.imtech.res.in/raghava/bcepred/bcepred_submission.html Bcepred] | ||
<br> | <br> | ||
| - | Result Predicited by | + | Result Predicited by [http://crdd.osdd.net/drugpedia/images/Rv3634.pdf]<br> |
====ABCpred Analysis==== | ====ABCpred Analysis==== | ||
Link to [http://www.imtech.res.in/raghava/abcpred/ABC_submission.html ABCpred]<br> | Link to [http://www.imtech.res.in/raghava/abcpred/ABC_submission.html ABCpred]<br> | ||
| - | Result Predicited by | + | Result Predicited by [http://crdd.osdd.net/drugpedia/images/Rv36341.pdf]<br> |
====IEDB Analysis==== | ====IEDB Analysis==== | ||
Link to [http://tools.immuneepitope.org/tools/bcell/iedb_input IEDB]<br> | Link to [http://tools.immuneepitope.org/tools/bcell/iedb_input IEDB]<br> | ||
| - | Result Predicited by | + | Result Predicited by [http://crdd.osdd.net/drugpedia/images/Rv36342.pdf]<br> |
=MHC Class-I Binder= | =MHC Class-I Binder= | ||
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Link to [http://www.imtech.res.in/raghava/nhlapred/comp.html nHLApred] | Link to [http://www.imtech.res.in/raghava/nhlapred/comp.html nHLApred] | ||
<br> | <br> | ||
| - | Result Predicited by [http://crdd.osdd.net/drugpedia/images/ | + | Result Predicited by [http://crdd.osdd.net/drugpedia/images/Rv36343.pdf]<br> |
==IEDB Analysis== | ==IEDB Analysis== | ||
Link to [http://tools.immuneepitope.org/analyze/html/mhc_processing.html IEDB] <br> | Link to [http://tools.immuneepitope.org/analyze/html/mhc_processing.html IEDB] <br> | ||
| - | Result Predicted by [http://crdd.osdd.net/drugpedia/images/ | + | Result Predicted by [http://crdd.osdd.net/drugpedia/images/Rv36344.txt]<br> |
| - | + | ||
=MHC Class-II Binder= | =MHC Class-II Binder= | ||
==Propred Analysis== | ==Propred Analysis== | ||
Link to [http://www.imtech.res.in/raghava/propred/ Propred]<br> | Link to [http://www.imtech.res.in/raghava/propred/ Propred]<br> | ||
| - | Result Predicted by | + | Result Predicted by [http://crdd.osdd.net/drugpedia/images/Rv36345.pdf]<br> |
Revision as of 08:20, 24 February 2010
| Rv3634c
| |
| Name | |
| galE1 | |
| Identifiers | |
| Swiss Prot | |
| Genbank | |
| PDB | ? |
| Chemical data | |
| Formula | C10H12ClNO2 [1] |
| Mol. wt. | 33550 Da |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Solubility | ? |
| Isoelectric-Point | 6.2 |
Contents |
General
POSSIBLY INVOLVED IN SYNTHESIS OF A-BAND COMMON ANTIGEN LIPOPOLYSACCHARIDE. FIRST OF THE THREE STEPS IN THE BIOSYNTHESIS OF GDP-FUCOSE FROM GDP-MANNOSE [CATALYTIC ACTIVITY: GDP-mannose = GDP-4-dehydro-6-deoxy-D-mannose + H2O].
Essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003) mutants available at TARGET website
Protein Sequence
>Rv3634c, TB.seq 4072667:4073608 MW:33550 VRALVTGAAGFIGSTLVDRLLADGHSVVGLDNFATGRATNLEHLADNSAHVFVEADIVTADLHAILEQHRPEVVFHLAAQ IDVRRSVADPQFDAAVNVIGTVRLAEAARQTGVRKIVHTSSGGSIYGTPPEYPTPETAPTDPASPYAAGKVAGEIYLNTF RHLYGLDCSHIAPANVYGPRQDPHGEAGVVAIFAQALLSGKPTRVFGDGTNTRDYVFVDDVVDAFVRVSADVGGGLRFNI GTGKETSDRQLHSAVAAAVGGPDDPEFHPPRLGDLKRSCLDIGLAERVLGWRPQIELADGVRRTVEYFRHKHTD
Human Homologue Blast Result
| subject ids | % identity | % positives | alignment length | evalue |
| sp|O95455.1 | 29 | 48 | 318 | 2e-34 |
| sp|Q8NBZ7.1 | 29 | 49 | 316 | 5e-34 |
| sp|Q14376.2 | 28 | 41 | 328 | 3e-17 |
| sp|O60547.1 | 26 | 42 | 342 | 8e-17 |
| sp|Q15738.2 | 24 | 40 | 356 | 1e-13 |
Alergen Protein
Link to Algpred
Non Allergen Predicted by AlgPred Server
Bacterial Toxin Prediction
Link to btxpred
No Hit Fountd by btxpred server.
Subcellular Location
Link to TBpred
Cytoplasmic
Antigens
No Hit Found in AntigenDB
No. Hit Found in IEDB
B cell Epitopes
BCEpred Analysis
Link to Bcepred
Result Predicited by [2]
ABCpred Analysis
Link to ABCpred
Result Predicited by [3]
IEDB Analysis
Link to IEDB
Result Predicited by [4]
MHC Class-I Binder
nHLAPred Analysis
Link to nHLApred
Result Predicited by [5]
IEDB Analysis
Link to IEDB
Result Predicted by [6]
MHC Class-II Binder
Propred Analysis
Link to Propred
Result Predicted by [7]
NetMHC-II Analysis
Link to NetMHC-II
Result Predicted by
External Links
- Database of Mycobacterium tuberculosis genome sequences and related information.
