Oxoglaucine
From DrugPedia: A Wikipedia for Drug discovery
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| IUPAC_name =N/A | | IUPAC_name =N/A | ||
| PubChem = 97662 | | PubChem = 97662 | ||
| + | |CAS Number = 5574-24-3) | ||
| DrugBank = | | DrugBank = | ||
| - | | ChemSpiderID = | + | | ChemSpiderID = 88148 |
| chemical_formula =C<sub>2</sub><sub>0</sub>H<sub>1</sub><sub>7</sub>NO<sub>5</sub> | | chemical_formula =C<sub>2</sub><sub>0</sub>H<sub>1</sub><sub>7</sub>NO<sub>5</sub> | ||
| molecular_weight = 351.35268 | | molecular_weight = 351.35268 | ||
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==Description== | ==Description== | ||
| - | + | oxoglaucine have been isolated from Annona cherimola 17 and from Croton hemiargyreus 89 respectively.the low doses (1 or 2 mg kg-1) oxoglaucine improved the outcome of Klebsiella pneumoniae infection, while at higher doses (10 or 20 mg kg-1) the substance caused an impairment of host resistance to infectious agent. | |
| - | + | ||
==General Properties== | ==General Properties== | ||
<b>*Molecular Weight</b> | <b>*Molecular Weight</b> | ||
Revision as of 09:43, 1 May 2009
| Oxoglaucine
| |
| Systematic (IUPAC) name | |
| N/A | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| ChemSpider | |
| Chemical data | |
| Formula | C20H17NO5 |
| Mol. mass | 351.35268 |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Description
oxoglaucine have been isolated from Annona cherimola 17 and from Croton hemiargyreus 89 respectively.the low doses (1 or 2 mg kg-1) oxoglaucine improved the outcome of Klebsiella pneumoniae infection, while at higher doses (10 or 20 mg kg-1) the substance caused an impairment of host resistance to infectious agent.
General Properties
*Molecular Weight
351.35268
*Molecular Formula
C20H17NO5
*IUPAC NAME
N/A
*Canonical Smiles
COC1=C(C2=C3C(=C1)C=CN=C3C(=O)C4=CC(=C(C=C42)OC)OC)OC
*Isomeric Smiles
N/A
*XLogP
2.7
*Topological Polar Surface Area
66.9
