Leukotriene C4
From DrugPedia: A Wikipedia for Drug discovery
| Line 12: | Line 12: | ||
{{Drugbox | {{Drugbox | ||
| - | | IUPAC_name = | + | | IUPAC_name = |
| - | + | | CAS_number = | |
| - | | CAS_number = | + | | CAS_supplemental = |
| - | | CAS_supplemental = | + | |
| ATC_suffix = | | ATC_suffix = | ||
| ATC_supplemental = | | ATC_supplemental = | ||
| - | | PubChem = | + | | PubChem = |
| - | | DrugBank = | + | | DrugBank = |
| ChemSpiderID = | | ChemSpiderID = | ||
| - | | chemical_formula = | + | | chemical_formula = |
| - | | molecular_weight = | + | | molecular_weight = |
| - | | smiles = | + | | smiles = |
| - | | synonyms = | + | | synonyms = |
| density = | | density = | ||
| - | | melting_point = | + | | melting_point = |
| boiling_point = | | boiling_point = | ||
| solubility = | | solubility = | ||
| Line 40: | Line 39: | ||
| routes_of_administration = | | routes_of_administration = | ||
}} | }} | ||
| + | |||
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990) | The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990) | ||
Revision as of 11:10, 20 February 2009
|
|
| Leukotriene C4
| |
| Systematic (IUPAC) name | |
| ? | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | ? |
| Chemical data | |
| Formula | ? |
| Mol. mass | ? |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990)
General Properties
*Molecular Weight
625.77
*Molecular Formula
C30H47N3O9S
*IUPAC NAME
(5S,6R,7E,9E,11Z,14Z)-6-[(2R)-2-[[(4S)-4-amino-5-hydroxy-5-oxopentanoyl]amino]-3-(carboxymethylamino)-3-oxopropyl]sulfanyl-5-hydroxyicosa-7,9,11,14-tetraenoic acid
*Canonical Smiles
CCCCCC=CCC=CC=CC=CC(C(CCCC(=O)O)O)SCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N
*Isomeric Smiles
CCCCCC=C/CC=C/C=C/C=C/[C@H]([C@H](CCCC(=O)O)O)SC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N
PhysioChemical Properties
*Melting Point
*LogP
*Water Solubility
