17-alpha-Hydroxyprogesterone
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES. | A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES. | ||
| + | [http://172.141.127.22/raghava/hmrbase/test_extract.php?db=arun&table=nphormonet&id=1004&show=SHOW-3D Show 3-D Structure] | ||
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==General Properties== | ==General Properties== | ||
Revision as of 06:25, 19 February 2009
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Contents |
Description
A metabolite of PROGESTERONE with a hydroxyl group at the 17-alpha position. It serves as an intermediate in the biosynthesis of HYDROCORTISONE and GONADAL STEROID HORMONES. Show 3-D Structure
General Properties
*Molecular Weight
330.46
*Molecular Formula
C21H30O3
*IUPAC NAME
(8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthren-3-one
*Canonical Smiles
CC(=O)C1(CCC2C1(CCC3C2CCC4=CC(=O)CCC34C)C)O
*Isomeric Smiles
CC(=O)[C@]1(CC[C@@H]2[C@@]1(CC[C@H]3[C@H]2CCC4=CC(=O)CC[C@]34C)C)O
PhysioChemical Properties
*Melting Point
222-223(EXP)
*LogP
3.17(EXP)
*Water Solubility
6.48(EXP) at 27C
