Insulin receptor7101)
From DrugPedia: A Wikipedia for Drug discovery
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==Function== | ==Function== | ||
This receptor binds insulin and has a tyrosine-protein kinase activity. | This receptor binds insulin and has a tyrosine-protein kinase activity. | ||
| - | + | [[category:Receptors]] | |
| - | [[ | + | [[Category:HMRbase]] |
Current revision
Contents |
[edit] Source Organism
Macaca mulatta (Rhesus macaque).
[edit] Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
[edit] Subcellular Localization
Membrane; Single-pass type I membrane protein.
[edit] Developmental Stage
[edit] Similarity
Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamily. Contains 2 fibronectin type-III domains. Contains 1 protein kinase domain.
[edit] Post translational Modification
Autophosphorylated on tyrosine residues in response to insulin (By similarity).
[edit] Function
This receptor binds insulin and has a tyrosine-protein kinase activity.
