Prostacyclin

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Revision as of 07:12, 13 February 2009

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A prostaglandin that is a powerful vasodilator and inhibits platelet aggregation. It is biosynthesized enzymatically from PROSTAGLANDIN ENDOPEROXIDES in human vascular tissue. The sodium salt has been also used to treat primary pulmonary hypertension (HYPERTENSION, PULMONARY).

General Properties

*Molecular Weight

352.47

*Molecular Formula

C₂₀H₃₂O₅

*IUPAC NAME

(5Z)-5-[(3aR,4R,5R,6aS)-5-hydroxy-4-[(E,3S)-3-hydroxyoct-1-enyl]-3,3a,4,5,6,6a-hexahydrocyclopenta[d]furan-2-ylidene]pentanoic acid

*Canonical Smiles

CCCCCC(C=CC1C(CC2C1CC(=CCCCC(=O)O)O2)O)O

*Isomeric Smiles

CCCCC[C@@H](C=C[C@H]1[C@@H](C[C@H]2[C@@H]1C/C(=C/CCCC(=O)O)/O2)O)O

PhysioChemical Properties

*Melting Point

*LogP

*Water Solubility

External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]KEGG Drug
• [4]Human Metabolome DataBase
• [5]Drugbank

Categories:Hormones