Dexamethasone

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Revision as of 07:10, 13 February 2009

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

An anti-inflammatory 9-fluoro-glucocorticoid.

General Properties

*Molecular Weight

392.46

*Molecular Formula

C₂₂H₂₉FO₅

*IUPAC NAME

(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC1CC2C3CCC4=CC(=O)C=CC4(C3(C(CC2(C1(C(=O)CO)O)C)O)F)C

*Isomeric Smiles

C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C

PhysioChemical Properties

*Melting Point

262(EXP)

*LogP

1.83(EXP)

*Water Solubility

89(EXP) at 25C

External Links

• [1]Pubchem
• [2]]KEGG Drug
• [3]Human Metabolome DataBase
• [4]Drugbank

Categories:Hormones