Betamethasone 17-Valerate
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
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The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity. | The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity. | ||
==General Properties== | ==General Properties== | ||
Revision as of 07:22, 19 February 2009
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Contents |
Description
The 17-valerate derivative of BETAMETHASONE. It has substantial topical anti-inflammatory activity and relatively low systemic anti-inflammatory activity.
General Properties
*Molecular Weight
476.58
*Molecular Formula
C27H37FO6
*IUPAC NAME
[(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] pentanoate
*Canonical Smiles
CCCCC(=O)OC1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)F)O)C)C)C(=O)CO
*Isomeric Smiles
CCCCC(=O)O[C@@]1([C@H](C[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)C)C(=O)CO
PhysioChemical Properties
*Melting Point
183-184(EXP)
*LogP
3.6(EXP)
*Water Solubility
9.29(EXP) at 25C
