5-OXO-ETE
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
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5-OXO-ETE | 5-OXO-ETE | ||
| + | Pubchem(5283159) | ||
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| + | RN given is for cpd without isomeric designation; an arachidonate metabolite which stimulates neutrophils to mobilize Ca and promotes PMN degranulation responses. | ||
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| + | '''KEGG Pathway'''(C14732) | ||
| + | *Arachidonic acid metabolism | ||
Ec50=4nM2 | Ec50=4nM2 | ||
Current revision
5-OXO-ETE Pubchem(5283159)
RN given is for cpd without isomeric designation; an arachidonate metabolite which stimulates neutrophils to mobilize Ca and promotes PMN degranulation responses.
KEGG Pathway(C14732)
- Arachidonic acid metabolism
Ec50=4nM2
This is important in MAP kinase,cPLA2,PI 3-Kinase siganal transduction pathways. The 5oxo-ETE receptor belong to the g-protein coupled receptor family as the action of this substance are blocked by the G-protein inhibitor pertusis toxin.
