Pregnenolone
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Revision as of 05:44, 31 October 2008
Pregnenolone
Pubchem(8955)
A 21-carbon steroid, derived from CHOLESTEROL and found in steroid hormone-producing tissues. Pregnenolone is the precursor to GONADAL STEROID HORMONES and the adrenal CORTICOSTEROIDS.
Drug Type: Small Molecule; Experimental
KEGG Pathway(C01953,D00143)
- C21-Steroid hormone metabolism
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 192 | deg C | EXP | |
| log P (octanol-water) | 4.22 | (none) | EXP | |
| Water Solubility | 7.06 | mg/L | 37 | EXP |
| Vapor Pressure | 1.03E-08 | mm Hg | 25 | EST |
| Henry's Law Constant | 1.17E-08 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 1.20E-10 | cm3/molecule-sec | 25 | EST |
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD | intraperitoneal | > 200mg/kg (200mg/kg) | Journal of Medicinal Chemistry. Vol. 11, Pg. 117, 1968. |
