CarboDB Lipopolysaccharide 1197
From DrugPedia: A Wikipedia for Drug discovery
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[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Brucella abortus 1119-3
[edit] Basic Structure
N/A
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Killed whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
B.ab.-6
[edit] Antibody type and class
IgM
[edit] Assay System
Whole cell agglutination, immunodiffusion, immunoblotting and ELISA
[edit] Cross-reactivity
This Mab cross-reacted with LPS and 0-chains of Y. enterocolitica and B. abortus and exhibited high ELISA titers with homologous and heterologous antigens, in addition to agglutinating activity for both bacteria
[edit] Proposed epitopes
this Mab was proposed to be directed to antigenic determinants present along the length of the polymeric O-chain
[edit] Proposed Utility
This Mab can be used to study the cell wall polysaccharide antigens of other Y. enterocolitica strains and are being evaluated for specific serological identification of B. abortus.