Ethaverine
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
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| + | Tetraethyl homolog of papaverine; smooth muscle relaxant; RN given refers to parent cpd; structure | ||
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| + | Ethaverine is a derivative of papaverine used in the treatment of peripheral vascular disease and is thought to cause vasodilation by reducing intracellular Ca2+ concentrations in vascular smooth muscle cells. | ||
==General Properties== | ==General Properties== | ||
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[http://crdd.osdd.net/raghava/biadb/detail.php?id=1129 Link to BIAdb Database] | [http://crdd.osdd.net/raghava/biadb/detail.php?id=1129 Link to BIAdb Database] | ||
| + | [[Category:BIAdb_old]] | ||
Current revision
| Ethaverine
| |
| Systematic (IUPAC) name | |
| 1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinolin-2-ium chloride | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| Chemical data | |
| Formula | C24H30ClNO4 |
| Mol. mass | 431.9523 |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
[edit] Description
Tetraethyl homolog of papaverine; smooth muscle relaxant; RN given refers to parent cpd; structure
Ethaverine is a derivative of papaverine used in the treatment of peripheral vascular disease and is thought to cause vasodilation by reducing intracellular Ca2+ concentrations in vascular smooth muscle cells.
[edit] General Properties
*Molecular Weight
431.9523
*Molecular Formula
C24H30ClNO4
*IUPAC NAME
1-[(3,4-diethoxyphenyl)methyl]-6,7-diethoxyisoquinolin-2-ium chloride
*Canonical Smiles
CCOC1=C(C=C(C=C1)CC2=[NH+]C=CC3=CC(=C(C=C32)OCC)OCC)OCC.[Cl-]
*Isomeric Smiles
N/A
*XLogP
N/A
*Topological Polar Surface Area
51.1
