Roemerine

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==Description==
==Description==
from root tubers of Stephania kwangsiensis H.S. Lo; RN given refers to (R)-isomer; synonym aporeine refers to (S)-isomer; structure in Merck Index, 9th ed, #779
from root tubers of Stephania kwangsiensis H.S. Lo; RN given refers to (R)-isomer; synonym aporeine refers to (S)-isomer; structure in Merck Index, 9th ed, #779
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(-)-roemerine, isolated from the leaves of Annona senegalensis, was found to enhance the cytotoxic response mediated by vinblastine with multidrug-resistant KB-V1 cells.
==General Properties==
==General Properties==

Current revision

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Roemerine
Systematic (IUPAC) name
N/A
Identifiers
CAS number  ?
ATC code  ?
PubChem 119204
Chemical data
Formula C18H17NO2
Mol. mass 279.33308
SMILES eMolecules & PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

[edit] Description

from root tubers of Stephania kwangsiensis H.S. Lo; RN given refers to (R)-isomer; synonym aporeine refers to (S)-isomer; structure in Merck Index, 9th ed, #779

(-)-roemerine, isolated from the leaves of Annona senegalensis, was found to enhance the cytotoxic response mediated by vinblastine with multidrug-resistant KB-V1 cells.

[edit] General Properties

*Molecular Weight

279.33308

*Molecular Formula

C18H17NO2

*IUPAC NAME

N/A

*Canonical Smiles

CN1CCC2=CC3=C(C4=C2C1CC5=CC=CC=C54)OCO3

*Isomeric Smiles

CN1CCC2=CC3=C(C4=C2[C@H]1CC5=CC=CC=C54)OCO3

*XLogP

3.3

*Topological Polar Surface Area

21.7

[edit] External Links

Link to BIAdb Database