Leukotriene B4
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
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The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990) | The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990) | ||
==General Properties== | ==General Properties== | ||
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*[http://www.hmdb.ca/metabolites/HMDB01085]Human Metabolome DataBase | *[http://www.hmdb.ca/metabolites/HMDB01085]Human Metabolome DataBase | ||
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[edit] Description
The major metabolite in neutrophil polymorphonuclear leukocytes. It stimulates polymorphonuclear cell function (degranulation, formation of oxygen-centered free radicals, arachidonic acid release, and metabolism). (From Dictionary of Prostaglandins and Related Compounds, 1990)
[edit] General Properties
*Molecular Weight
336.47
*Molecular Formula
C20H32O4
*IUPAC NAME
(5S,6Z,8E,10E,12R,14Z)-5,12-dihydroxyicosa-6,8,10,14-tetraenoic acid
*Canonical Smiles
CCCCCC=CCC(C=CC=CC=CC(CCCC(=O)O)O)O
*Isomeric Smiles
CCCCCC=C/C[C@H](C=CC=CC=C/[C@H](CCCC(=O)O)O)O
[edit] PhysioChemical Properties
*Melting Point
*LogP
*Water Solubility
