CarboDB Antigen 5 1756
From DrugPedia: A Wikipedia for Drug discovery
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[edit] Carbohydrate Name
Antigen 5
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Mycobacterium tuberculosis
[edit] Basic Structure
Antigen 5 is a well known 35,000-dalton glycoprotein of Mycobacteriun tuberculosis
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
M. tuberculosis culture filtrate
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab TB-C-11
[edit] Antibody type and class
IgM
[edit] Assay System
ELISA, immunoabsorbent affinity chromatography
[edit] Cross-reactivity
This Mab is highly cross-reactive and cross-reacted with M. kansasii, M. gordonae, M. scrofulaceum and M. intracellulare and also cross-reacted with antigen 6 from Mycobacterium tuberculosis
[edit] Proposed epitopes
Arabinomannan and arabinogalactan residues seemed to be a part of the epitope
[edit] Proposed Utility
This Mab would allow the purification of important mycobacterial antigens antigens