Colchicine analog
From DrugPedia: A Wikipedia for Drug discovery
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| PubChem = 84075 | | PubChem = 84075 | ||
| DrugBank = | | DrugBank = | ||
| - | | ChemSpiderID = | + | | ChemSpiderID = 75852 |
| chemical_formula =C<sub>3</sub><sub>0</sub>H<sub>3</sub><sub>3</sub>NO<sub>9</sub> | | chemical_formula =C<sub>3</sub><sub>0</sub>H<sub>3</sub><sub>3</sub>NO<sub>9</sub> | ||
| molecular_weight = 551.58432 | | molecular_weight = 551.58432 | ||
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111 | 111 | ||
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| + | ==Toxicity== | ||
| + | Organism Test Type Route Reported Dose (Normalized Dose) Effect Source | ||
| + | |||
| + | mouse LDLo intramuscular 99288ug/kg (99.288mg/kg) Journal of Medicinal Chemistry. Vol. 26, Pg. 1365, 1983. | ||
==External Links== | ==External Links== | ||
Revision as of 04:23, 5 May 2009
| Colchicine analog
| |
| Systematic (IUPAC) name | |
| 3,4,5-trimethoxy-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]benzamide | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| ChemSpider | |
| Chemical data | |
| Formula | C30H33NO9 |
| Mol. mass | 551.58432 |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
Contents |
Description
General Properties
*Molecular Weight
551.58432
*Molecular Formula
C30H33NO9
*IUPAC NAME
3,4,5-trimethoxy-N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[d]heptalen-7-yl]benzamide
*Canonical Smiles
COC1=CC=C2C(=CC1=O)C(CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)C4=CC(=C(C(=C4)OC)OC)OC
*Isomeric Smiles
COC1=CC=C2C(=CC1=O)[C@H](CCC3=CC(=C(C(=C32)OC)OC)OC)NC(=O)C4=CC(=C(C(=C4)OC)OC)OC
*XLogP
2.6
*Topological Polar Surface Area
111
Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LDLo intramuscular 99288ug/kg (99.288mg/kg) Journal of Medicinal Chemistry. Vol. 26, Pg. 1365, 1983.
