PreClinical Trial
From DrugPedia: A Wikipedia for Drug discovery
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(New page: Preclinical Testing: The compound is tested for safety and efficacy in laboratory and animal studies.Before testing compound on humans in clinical trials, scientists must show that the co...) |
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Preclinical Testing: | Preclinical Testing: | ||
| - | The compound is tested for safety and efficacy in laboratory and animal studies.Before testing compound on humans in clinical trials, scientists must show that the compound do not present an unacceptable level of risk, given the expected therapeutic benefit. | + | The compound is tested for safety and efficacy in laboratory and animal studies.Before testing compound on humans in clinical trials, scientists must show that the compound do not present an unacceptable level of risk, given the expected therapeutic benefit.The twenty or so perfected compounds are evaluated both in vitro and in vivo. Of these, between one and five will have the characteristics required for Phase-I clinical studies.This process will take about 4-6 months. |
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| + | Preclinical Testing Involves: | ||
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| + | #Pharmacology | ||
| + | #Toxicology | ||
| + | #Preformulation | ||
| + | #Formulation | ||
| + | #Analytical | ||
| + | #Pharmacokinetics | ||
Revision as of 04:37, 31 July 2008
Preclinical Testing:
The compound is tested for safety and efficacy in laboratory and animal studies.Before testing compound on humans in clinical trials, scientists must show that the compound do not present an unacceptable level of risk, given the expected therapeutic benefit.The twenty or so perfected compounds are evaluated both in vitro and in vivo. Of these, between one and five will have the characteristics required for Phase-I clinical studies.This process will take about 4-6 months.
Preclinical Testing Involves:
- Pharmacology
- Toxicology
- Preformulation
- Formulation
- Analytical
- Pharmacokinetics
