Fluocortolone
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
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A glucocorticoid with anti-inflammatory activity used topically for various skin disorders. | A glucocorticoid with anti-inflammatory activity used topically for various skin disorders. | ||
==General Properties== | ==General Properties== |
Revision as of 09:08, 19 February 2009
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Contents |
Description
A glucocorticoid with anti-inflammatory activity used topically for various skin disorders.
General Properties
*Molecular Weight
376.46
*Molecular Formula
C22H29FO4
*IUPAC NAME
(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-fluoro-11-hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
*Canonical Smiles
CC1CC2C3CC(C4=CC(=O)C=CC4(C3C(CC2(C1C(=O)CO)C)O)C)F
*Isomeric Smiles
C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@H]3[C@H](C[C@@]2([C@H]1C(=O)CO)C)O)C)F
PhysioChemical Properties
*Melting Point
188(EXP)
*LogP
2.06(EST)
*Water Solubility
290(EXP) at 37C