Fluocinolone Acetonide
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
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A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732) | A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732) | ||
==General Properties== | ==General Properties== | ||
Revision as of 09:07, 19 February 2009
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Description
A glucocorticoid derivative used topically in the treatment of various skin disorders. It is usually employed as a cream, gel, lotion, or ointment. It has also been used topically in the treatment of inflammatory eye, ear, and nose disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p732)
General Properties
*Molecular Weight
452.49
*Molecular Formula
C24H30F2O6
*IUPAC NAME
*Canonical Smiles
CC1(OC2CC3C4CC(C5=CC(=O)C=CC5(C4(C(CC3(C2(O1)C(=O)CO)C)O)F)C)F)C
*Isomeric Smiles
CC1(O[C@@H]2C[C@H]3[C@@H]4C[C@@H](C5=CC(=O)C=C[C@@]5([C@]4([C@H](C[C@@]3([C@@]2(O1)C(=O)CO)C)O)F)C)F)C
PhysioChemical Properties
*Melting Point
265-266(EXP)
*LogP
2.48(EXP)
*Water Solubility
11(EST) at 25C
