Renin

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Revision as of 08:22, 13 February 2009

Contents 1 Description 2 Source Organism 3 Taxomomy 4 Subcellular Localization 5 Developmental Stage 6 Similarity 7 Post translational Modification 8 Function 9 GeneID

Description

Renin-1; EC=3.4.23.15;Alternative Name: Angiotensinogenase;Alternative Name: Kidney renin;Precursor

Source Organism

Mus musculus (Mouse).

Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi;Muroidea; Muridae; Murinae; Mus.

Subcellular Localization

Secreted (By similarity). Membrane (By similarity). Note=Associated to membranes via binding to ATP6AP2 (By similarity).

Developmental Stage

Similarity

Belongs to the peptidase A1 family.

Post translational Modification

Function

Renin is a highly specific endopeptidase, whose only known function is to generate angiotensin I from angiotensinogen in the plasma, initiating a cascade of reactions that produce an elevation of blood pressure and increased sodium retention by the kidney.

GeneID

19701

Categories:Hormones