Muellerian-inhibiting factor
From DrugPedia: A Wikipedia for Drug discovery
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Contents |
Description
Muellerian-inhibiting factor precursor (MIS) (Anti-Muellerian hormone)(AMH) (Muellerian-inhibiting substance).
Source Organism
Bos taurus (Bovine).
Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Cetartiodactyla; Ruminantia;Pecora; Bovidae; Bovinae; Bos.
Subcellular Localization
Secreted protein.
Developmental Stage
Similarity
Belongs to the TGF-beta family.
Post translational Modification
Function
This glycoprotein, produced by the Sertoli cells of the testis, causes regression of the Muellerian duct. It is also able to inhibit the growth of tumors derived from tissues of Muellerian duct origin
GeneID
280718