Nuclear hormone receptor HR78

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Contents 1 Source Organism 2 Taxomomy 3 Subcellular Localization 4 Developmental Stage 5 Similarity 6 Post translational Modification 7 Function

Source Organism

Drosophila melanogaster (Fruit fly).

Taxomomy

Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila.

Subcellular Localization

Nucleus.

Developmental Stage

Highest expression in third instar larvae and prepupae.

Similarity

Belongs to the nuclear hormone receptor family. NR2 subfamily. Contains 1 nuclear receptor DNA-binding domain.

Post translational Modification

Function

Binds to direct repeats of the sequence 5'-AGGTCA-3'. Inhibits the ecdysone response. Plays an essential role in regulating molting of the tracheal cuticle during larval development.

Categories:Receptors