Prednisolone

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Revision as of 07:12, 13 February 2009

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

Description

A glucocorticoid with the general properties of the corticosteroids. It is the drug of choice for all conditions in which routine systemic corticosteroid therapy is indicated, except adrenal deficiency states.

General Properties

*Molecular Weight

360.44

*Molecular Formula

C₂₁H₂₈O₅

*IUPAC NAME

(8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one

*Canonical Smiles

CC12CC(C3C(C1CCC2(C(=O)CO)O)CCC4=CC(=O)C=CC34C)O

*Isomeric Smiles

C[C@]12C[C@@H]([C@H]3[C@H]([C@@H]1CC[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@]34C)O

PhysioChemical Properties

*Melting Point

235(EXP)

*LogP

1.62(EXP)

*Water Solubility

223(EXP) at 25C

External Links

• [1]Pubchem
• [2]KEGG Compound
• [3]KEGG Drug
• [4]Drugbank

Categories:Hormones