Androstenediol

From DrugPedia: A Wikipedia for Drug discovery

(Difference between revisions)
Jump to: navigation, search
m
(New page: '''Androstenediol''' Pubchem(10634) An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the re...)
(2 intermediate revisions not shown.)
Line 1: Line 1:
 +
'''Androstenediol'''
 +
Pubchem(10634)
-
<table align='right' border=1>
+
An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).
-
<tr><td>
+
-
<jmol><jmolApplet>
+
-
<size>200</size>
+
-
<script>spin on;color atoms amino;</script>
+
-
<uploadedFileContents>NPH116.SDF</uploadedFileContents>
+
-
<color>black</color>
+
-
</jmolApplet>
+
-
</jmol>
+
-
</td></tr></table>
+
-
==Description==
+
-
An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or   the ADRENAL GLANDS. Androstenediol, derived from   DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group   (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by   the oxidation of the 3-beta hydroxyl group to a 3-keto group   (3-HYDROXYSTEROID DEHYDROGENASES).
+
-
==General Properties==
+
-
<b>*Molecular Weight</b>
+
'''Drug Type''':  Small Molecule; Illicit; Experimental
-
290.44
+
'''KEGG Pathway'''(C04295,D00179)
 +
*Androgen and estrogen metabolism
-
<b>*Molecular Formula</b>
+
Physical Property  Value  Units  Temp (deg C)  Source
-
 
+
|log P (octanol-water)
-
C<sub>1</sub><sub>9</sub>H<sub>3</sub><sub>0</sub>O<sub>2</sub>
+
|4.580
-
 
+
|(none)  
-
<b>*IUPAC NAME</b>
+
|  
-
 
+
|EST
-
(3S,8R,9S,10R,13S,14S,17S)-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthrene-3,17-diol
+
|Atmospheric OH Rate Constant
-
 
+
|1.24E-10
-
<b>*Canonical Smiles</b>
+
|cm3/molecule-sec
-
 
+
|25
-
CC12CCC3C(C1CCC2O)CC=C4C3(CCC(C4)O)C
+
|EST
-
 
+
|-
-
<b>*Isomeric Smiles</b>
+
|}
-
 
+
-
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CC=C4[C@@]3(CC[C@@H](C4)O)C
+
-
 
+
-
 
+
-
==PhysioChemical Properties==
+
-
 
+
-
<b>*Melting Point</b>
+
-
 
+
-
 
+
-
 
+
-
<b>*LogP</b>
+
-
 
+
-
4.58(EST)
+
-
 
+
-
<b>*Water Solubility</b>
+
-
 
+
-
 
+
-
 
+
-
==External Links==
+
-
*[http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=10634]Pubchem
+
-
*[http://www.genome.jp/dbget-bin/www_bget?compound+C04295]]KEGG Compound
+
-
*[http://www.genome.jp/dbget-bin/www_bget?drug+D00179]]KEGG Drug
+
-
*[http://www.hmdb.ca/metabolites/HMDB03818]Human Metabolome DataBase
+
-
 
+
-
 
+
-
[[Categories:Hormones]]
+

Revision as of 09:55, 31 October 2008

Androstenediol

Pubchem(10634)

An intermediate in TESTOSTERONE biosynthesis, found in the TESTIS or the ADRENAL GLANDS. Androstenediol, derived from DEHYDROEPIANDROSTERONE by the reduction of the 17-keto group (17-HYDROXYSTEROID DEHYDROGENASES), is converted to TESTOSTERONE by the oxidation of the 3-beta hydroxyl group to a 3-keto group (3-HYDROXYSTEROID DEHYDROGENASES).

Drug Type: Small Molecule; Illicit; Experimental

KEGG Pathway(C04295,D00179)

  • Androgen and estrogen metabolism

Physical Property Value Units Temp (deg C) Source |log P (octanol-water) |4.580 |(none) | |EST |Atmospheric OH Rate Constant |1.24E-10 |cm3/molecule-sec |25 |EST |- |}

Retrieved from "http://277988.efsst.group/drugpedia/index.php/Androstenediol"