Aldosterone

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(New page: '''ALDOSTERONE''' Pubchem(5839) A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of pot...)
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'''ALDOSTERONE'''
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Pubchem(5839)
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A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.
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==Description==
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A hormone secreted by the ADRENAL CORTEX that regulates electrolyte   and water balance by increasing the renal retention of sodium and the   excretion of potassium.
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==General Properties==
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<b>*Molecular Weight</b>
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'''KEGG Pathway'''(C01780)
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*C21-Steroid hormone metabolism
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360.44
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Physical Property  Value  Units  Temp (deg C)  Source
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|Melting Point
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<b>*Molecular Formula</b>
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|166.5
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|deg C
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C<sub>2</sub><sub>1</sub>H<sub>2</sub><sub>8</sub>O<sub>5</sub>
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|  
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|EXP
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<b>*IUPAC NAME</b>
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|-
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|log P (octanol-water)
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(8S,9S,10R,11S,13R,14S,17S)-11-hydroxy-17-(2-hydroxyacetyl)-10-methyl-3-oxo-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthrene-13-carbaldehyde
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|1.08
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|(none)
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<b>*Canonical Smiles</b>
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| 
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|EXP
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CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4C(=O)CO)C=O)O
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|-
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|Water Solubility
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<b>*Isomeric Smiles</b>
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|51.2
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|mg/L
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C[C@]12CCC(=O)C=C1CC[C@@H]3[C@@H]2[C@H](C[C@]4([C@H]3CC[C@@H]4C(=O)CO)C=O)O
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|37
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|EXP
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|-
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==PhysioChemical Properties==
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|Vapor Pressure
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|1.25E-12
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<b>*Melting Point</b>
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|mm Hg
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|25
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166.5(EXP)
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|EST
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|-
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<b>*LogP</b>
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|Henry's Law Constant
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|1.81E-13
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1.08(EXP)
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|atm-m3/mole
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|25
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<b>*Water Solubility</b>
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|EST
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|-
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51.2(EXP) at 37C
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|Atmospheric OH Rate Constant
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|1.49E-10
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==External Links==
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|cm3/molecule-sec
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*[http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5839]Pubchem
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|25
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*[http://www.genome.jp/dbget-bin/www_bget?compound+C01780]]KEGG Compound
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|EST
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*[http://www.hmdb.ca/metabolites/HMDB00037]Human Metabolome DataBase
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|-
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*[http://www.drugbank.ca/drugs/DB04630]Drugbank
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|}
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[[Categories:Hormones]]
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Revision as of 09:46, 31 October 2008

ALDOSTERONE

Pubchem(5839)

A hormone secreted by the ADRENAL CORTEX that regulates electrolyte and water balance by increasing the renal retention of sodium and the excretion of potassium.

KEGG Pathway(C01780)

  • C21-Steroid hormone metabolism

Physical Property Value Units Temp (deg C) Source |Melting Point |166.5 |deg C | |EXP |- |log P (octanol-water) |1.08 |(none) | |EXP |- |Water Solubility |51.2 |mg/L |37 |EXP |- |Vapor Pressure |1.25E-12 |mm Hg |25 |EST |- |Henry's Law Constant |1.81E-13 |atm-m3/mole |25 |EST |- |Atmospheric OH Rate Constant |1.49E-10 |cm3/molecule-sec |25 |EST |- |}

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