Androstenedione
From DrugPedia: A Wikipedia for Drug discovery
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'''Drug Type''': Small Molecule; Illicit; Experimental | '''Drug Type''': Small Molecule; Illicit; Experimental | ||
{| border="1;width:100%; height:200px;style=text-align:center" | {| border="1;width:100%; height:200px;style=text-align:center" | ||
| - | |+'''List of PDB files having | + | |+'''List of PDB files having Androstenedione as a Ligand:''' |
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! style="background:brown; color:white" |MMDB ID | ! style="background:brown; color:white" |MMDB ID | ||
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| - | Physical Property | + | {| border="1;width:100%; height:200px;style=text-align:center" |
| + | |+'''Physiochemical properties of Androstenedione:''' | ||
| + | |- | ||
| + | ! style="background:brown; color:white" |Physical Property | ||
| + | ! style="background:brown; color:white" |Value | ||
| + | ! style="background:brown; color:white" |Units | ||
| + | ! style="background:brown; color:white" |Temp (deg C) | ||
| + | ! style="background:brown; color:white" |Source | ||
| + | |- | ||
|Melting Point | |Melting Point | ||
|158 | |158 | ||
Revision as of 09:07, 30 October 2008
Androstenedione Pubchem(6128) A delta-4 C19 steroid that is produced not only in the TESTIS, but also in the OVARY and the ADRENAL CORTEX. Depending on the tissue type, androstenedione can serve as a precursor to TESTOSTERONE as well as ESTRONE and ESTRADIOL.
KEGG Pathway(C00280,D00051)
- Androgen and estrogen metabolism
- Prostate cancer
Drug Type: Small Molecule; Illicit; Experimental
| MMDB ID | PDB ID | Reference |
|---|---|---|
| 28531 | 1QYX | Shi R, Lin SXCofactor hydrogen bonding onto the protein main chain is conserved in the short chain dehydrogenase/reductase family and contributes to nicotinamide orientationJ. Biol. Chem. v279, p.16778-16785 |
| Physical Property | Value | Units | Temp (deg C) | Source |
|---|---|---|---|---|
| Melting Point | 158 | deg C | EXP | |
| log P (octanol-water) | 2.75 | (none) | EXP | |
| Water Solubility | 57.8 | mg/L | 25 | EXP |
| Vapor Pressure | 2.46E-06 | mm Hg | 25 | EST |
| Henry's Law Constant | 3.68E-08 | atm-m3/mole | 25 | EST |
| Atmospheric OH Rate Constant | 1.11E-10 | cm3/molecule-sec | 25 | EST |
