Steroid

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Current revision

Table I:
S.No IDENTIFIER NAME FORMULA PDB_ID RECEPTOR TYPE
1 R18 (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11- TRIEN-3-ONE C19H24O2 1XQ3,1XQ2,1E3G,2ao6 ANDROGEN
2 ZK5 9ALPHA-FLUOROCORTISOL C21H29FO5 1GS4 ANDROGEN AGONIST
3 17H 17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA- 4,9,11-TRIEN-3-ONE C21H28O2 2amb ANDROGEN
4 TES TESTOSTERONE C19H28O2 2am9,2q7i,2q7k,2q7j ANDROGEN
5 DHT 5-ALPHA-DIHYDROTESTOSTERONE C19H30O2 2ama,1i37,1i38,1t5z,1t63,1t65,1t73,1t74,1t75,1t76,1t79,1t7f,1t7m,1t7r,1t7t,1xj7,2piv,2piw,2pkl,2qpy,2z4j,2pio,2pip,2piq,2pir,2pit,2piu,2pix,1d2s ANDROGEN
6 LG7 4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE C17H13N3O3 2ihq ANDROGEN
7 HYQ REL-(3AR,4S,7R,7AS)-3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE C20H18N2O4 1xnn ANDROGEN
8 HFT HYDROXYFLUTAMIDE C11H11F3N2O4 2ax6 ANDROGEN
9 8NH 2-CHLORO-4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-3-METHYLBENZONITRILE C14H12ClN3O3 2nw4 ANDROGEN
10 FHM S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE C17H14F4N2O5 2ax7,2ax8,2axa ANDROGEN
11 BHM (R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE C11H10BrF3N2O4 2ax9 ANDROGEN
12 I98 R-BICALUTAMIDE C18H14F4N2O4S 1z95 ANDROGEN
13 CA4 CYPROTERONE ACETATE C24H29ClO4 2oz7 ANDROGEN
14 ENM (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE C27H36F2O3 2pnu ANDROGEN
15 LGD 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE C14H9F9N2O 2hvc ANDROGEN
16 B5R (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano- 3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide C18H13ClF4N2O3 3b5r ANDROGEN
17 3B6 (2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)- 2-hydroxy-2-methylpropanamide C18H14IN3O3 3b65 ANDROGEN
18 B66 4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile C18H16F3N3O5 3b66 ANDROGEN
19 B67 (2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide C17H10F8N2O5 3b67 ANDROGEN
20 B68 (2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide C19H18F3N3O6 3b68 ANDROGEN
21 AON 5-ALPHA-ANDROSTANE-3-BETA,17-ALPHA-DIOL C19H32O2 1lhn ANDROGEN
22 AOM 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL C19H32O2 1lho ANDROGEN
23 EST ESTRADIOL C18H24O2 1A52,1ERE,1G50,1GWR,1PCG,1QKT,1QKU,2OCF,2J7X ESTROGEN
24 RAL RALOXIFENE C28H27NO4S 1ERR,2JFA,1QK ESTROGEN
25 ZTW RALOXIFENE CORE C14H10O2S 1GWQ ESTROGEN AGONIST
26 ETC (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE- 2,8-DIOL C22H24O2 1L2I,1L2J ESTROGEN
27 GW5 (2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRYLIC ACID C25H22O2 1R5K ESTROGEN
28 E4D (2S,3R)-2-(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-2,3-DIHYDRO-3-(4-HYDROXYPHENYL)BENZO[B][1,4]OXATHIIN-6-OL C27H29NO4S 1SJ0 ESTROGEN
29 PTI 2-PHENYL-1-[4-(2-PIPERIDIN-1-YL-ETHOXY)-PHENYL]-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL C28H32N2O2 1UOM ESTROGEN ANTAGONIST
30 244 [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN- 7-YL]ACETONITRILE C16H11NO3 1X7E ESTROGEN
31 GEN GENISTEIN C15H10O5 1X7R,2QA8,1QKM,1X7J ESTROGEN
32 AIH (2S,3R)-2-(4-{2-[(3R,4R)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL C28H31NO4S 1XP1 ESTROGEN
33 AIU (2S,3R)-2-(4-{2-[(3S,4S)-3,4-DIMETHYLPYRROLIDIN- 1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL C28H31NO4S 1XP6 ESTROGEN
34 AIJ (2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2S)-2-PYRROLIDIN-1-YLPROPYL]OXY}PHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL C27H29NO4S 1XP9 ESTROGEN
35 AIT (2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2R)-2-PYRROLIDIN-1-YLPROPYL]OXY}PHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL C27H29NO4S 1XPC ESTROGEN
36 AEJ (1S)-1-{4-[(9AR)-OCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZIN-2-YL]PHENYL}-2-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLIN-6-OL C29H33N3O 1XQC ESTROGEN
37 CM4 (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1YLETHOXY)PHENYL]CHROMAN-6-OL C28H31NO4 1YIM ESTROGEN
38 CM3 (2R,3R,4S)-5-FLUORO-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL C29H32FNO4 1YIN ESTROGEN
39 689 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL C18H24O3 1ZKY ESTROGEN
40 L4G 6-(4-METHYLSULFONYL-PHENYL)-5-[4-(2-PIPERIDIN- 1-YLETHOXY)PHENOXY]NAPHTHALEN-2-OL C30H31NO5S 2AYR ESTROGEN
41 458 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL- 3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL C16H20O3 2BIV ESTROGEN
42 17M 17-METHYL-17-ALPHA-DIHYDROEQUILENIN C19H22O2 2B1Z ESTROGEN
43 OHT 4-HYDROXYTAMOXIFEN C26H29NO2 2BJ4,2JF9,3ERT,2FSZ ESTROGEN
44 459 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL- 3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL C17H24O3 2FAI ESTROGEN
45 T3O 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON- 7-EN-2-YL]PHENOL C17H22O2 2G44 ESTROGEN
46 DRQ (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1- YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL C22H30O2 2G5O ESTROGEN
47 I0G (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B- HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL C18H18O3 2I0J,2I0G ESTROGEN
48 IOG N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]- 2-[2-PHENYL-6-(2-PIPERIDIN-1-YLETHOXY)-1H- INDOL-3-YL]ACETAMIDE C33H39N3O3 2IOG ESTROGEN
49 IOK N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]- 2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE C26H26N2O2 2IOK ESTROGEN
50 C3D (5R,6S)-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]- 5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL C28H31NO2 2OUZ ESTROGEN
51 EZT (17BETA)-17-{(E)-2-[2-(TRIFLUOROMETHYL)PHENYL]VINYL}ESTRA- 1(10),2,4-TRIENE-3,17-DIOL C27H29F3O2 2P15 ESTROGEN
52 WST (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B- HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL C18H18O3 2POG ESTROGEN
53 A48 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL C26H29BF3NO 2Q6J ESTROGEN
54 DC8 (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)- 1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN- 8-OL C18H16F2O3 2Q70 ESTROGEN
55 KN2 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3- DIOL C13H10N2O3 2QA6 ESTROGEN
56 EI1 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5- OL C15H14N2O2 2QAB ESTROGEN
57 JJ3 (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL C20H22O4 2QE4,2JJ3 ESTROGEN
58 EED (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL C20H28O3 2QGT ESTROGEN
59 EES 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL C13H9ClN2O2 2QGW ESTROGEN
60 ODE DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)- 7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE C24H24O7 2QH6 ESTROGEN
61 HZ3 dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)- 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate C22H18O7 2QR9 ESTROGEN
62 1HP 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin- 6-yl)phenol C13H12O 2QSE ESTROGEN
63 PIQ 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE C13H12N4 2QXM ESTROGEN
64 LLB [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien- 3-yl]{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl}methanone C29H29NO4S 2R6W ESTROGEN
64 LLC [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien- 3-yl][4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone C27H25NO4S 2R6Y ESTROGEN
66 SAH S-ADENOSYL-L-HOMOCYSTEINE C14H20N6O5S 3CMB ESTROGEN
67 DES DIETHYLSTILBESTROL C18H20O2 3ERD ESTROGEN
68 AOE N-BUTYL-11-[(7R,8R,9S,13S,14S,17S)-3,17-DIHYDROXY-13-METHYL-7,8,9,11,12,13,14,15,16,17-DECAHYDRO-6H-CYCLOPENTA[A]PHENANTHREN-7-YL]-N-METHYLUNDECANAMIDE C34H55NO3 1HJ1 ESTROGEN
69 E3O (16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE- 3,16,17-TRIOL C18H24O3 2J7Y ESTROGEN
70 MON 4-(2-{[4-{[3-(4-CHLOROPHENYL)PROPYL]SULFANYL}- 6-(1-PIPERAZINYL)-1,3,5-TRIAZIN-2-YL]AMINO}ETHYL)PHENOL C24H29ClN6OS 1NDE ESTROGEN
71 272 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL C13H9NO4 1U3Q ESTROGEN
72 338 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL C17H11NO3 1U3R ESTROGEN
73 797 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL C17H11NO3 1U3S ESTROGEN
74 397 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL C14H10O3 1U9E ESTROGEN
75 697 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN- 7-CARBONITRILE C15H9NO3 1X76 ESTROGEN
76 244 [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE C16H11NO3 1X78 ESTROGEN
77 41 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3- BENZOXAZOL-5-OL C15H10FNO3 1X7B ESTROGEN
78 4NA 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL C16H11ClO2 1YY4 ESTROGEN
79 196 3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1- NAPHTHONITRILE C17H10FNO2 1YYE ESTROGEN
80 789 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H- INDEN-1-ONE C15H9BrO3 1ZAF ESTROGEN
81 FBR (9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a- tetrahydro-3H-fluoren-3-one C17H19Br 2GIU ESTROGEN
82 555 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME C17H13NO2 2NV7 ESTROGEN
83 DC8 (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL C18H16F2O3 2Z4B ESTROGEN
84 47 1-CYCLOHEXYL-N-{[1-(4-METHYLPHENYL)-1H-INDOL-3-YL]METHYL}METHANAMINE C23H28N2 2PJL ESTROGEN-RELATED
85 DES DIETHYLSTILBESTROL C18H20O2 1S9P ESTROGEN-RELATED
86 OHT 4-HYDROXYTAMOXIFEN C26H29NO2 1X9Q,1VJB,1GPU ESTROGEN-RELATED
87 2OH 4,4'-PROPANE-2,2-DIYLDIPHENOL C15H16O2 2E2R,2P7G,2P7Z ESTROGEN-RELATED
88 TXF (Z)-4-(1-{4-[2-(DIMETHYLAMINO)ETHOXY]PHENYL}-5-HYDROXY-2-PHENYLPENT-1-ENYL)PHENOL C27H31NO3 2EWP ESTROGEN-RELATED
89 1BA 4-HYDROXY-N'-(4-ISOPROPYLBENZYL)BENZOHYDRAZIDE C17H20N2O2 1GPP ESTROGEN-RELATED
90 43M 4-CHLORO-3-METHYLPHENOL C7H7ClO 2P7A ESTROGEN-RELATED
91 DEX DEXAMETHASONE C22H29FO5 1M2Z,1P93 GLUCOCORTICOID AGONIST
92 486 11-(4-DIMETHYLAMINO-PHENYL)-17-HYDROXY-13-METHYL-17-PROP-1-YNYL-1,2,6,7,8,11,12,13,14,15,16,17-DODECAHYDRO-CYCLOPENTA[A]PHENANTHREN-3-ONE C29H35NO2 1NHZ GLUCOCORTICOID ANTAGONIST
93 DAY 1-[(1R,2R,3aS,3bS,10aR,10bS,11S,12aS)-1,11-dihydroxy-2,5,10a,12a-tetramethyl-7-phenyl-1,2,3,3a,3b,7,10,10a,10b,11,12,12a-dodecahydrocyclopenta[5,6]naphtho[1,2-f]indazol-1-yl]-2-hydroxyethanone C30H36N2O4 3BQD GLUCOCORTICOID
94 GW6 (6alpha,11alpha,14beta,16alpha,17alpha)-6,9-difluoro-17-{[(fluoromethyl)sulfanyl]carbonyl}-11-hydroxy-16-methyl-3-oxoandrosta-1,4-dien-17-ylfuran-2-carboxylate C27H29F3O6S 3CLD GLUCOCORTICOID
95 1CA DESOXYCORTICOSTERONE C21H30O3 1Y9R,2AA7,2ABI MINERALCORTICOID
96 STR PROGESTERONE C21H30O2 1YA3,2AA5,2AA6 MINERALCORTICOID
97 C0R CORTICOSTERONE C21H30O4 2A3I MINERALCORTICOID
98 AS4 ALDOSTERONE C21H28O5 2AA2 MINERALCORTICOID
99 PDN 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE C21H26O5 2AAX MINERALCORTICOID
100 SNL SPIRONOLACTONE C24H32O4S 2AB2,2OAX MINERALCORTICOID
101 STR PROGESTERONE C21H30O2 1A28 PROGESTRONE AGONIST
102 R18 (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE C19H24O2 1E3K PROGESTRONE AGONIST
103 NDR NORETHINDRONE C20H22O2 1SQN PROGESTRONE
104 MOF MOMETASONE FUROATE C27H30Cl2O6 1SR7 PROGESTRONE
105 T98 5-(4,4-DIMETHYL-2-THIOXO-1,4-DIHYDRO-2H-3,1-BENZOXAZIN-6-YL)-1-METHYL-1H-PYRROLE-2-CARBONITRILE C16H15N3OS 1ZUC PROGESTRONE
106 AS0 4-[(11BETA,17BETA)-17-METHOXY-17-(METHOXYMETHYL)-3-OXOESTRA-4,9-DIEN-11-YL]BENZALDEHYDEOXIME C28H35NO4 2OVH,2OVM PROGESTRONE
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