Steroid
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
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! style="background:brown; color:white" |S.No | ! style="background:brown; color:white" |S.No | ||
| + | ! style="background:brown; color:white" |IDENTIFIER | ||
| + | ! style="background:brown; color:white" |NAME | ||
| + | ! style="background:brown; color:white" |PDB_ID | ||
| + | ! style="background:brown; color:white" |RECEPTOR | ||
|- | |- | ||
|1 | |1 | ||
|R18 | |R18 | ||
| + | |(17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11- TRIEN-3-ONE | ||
|C19H24O2 | |C19H24O2 | ||
|1XQ3,1XQ2,1E3G,2ao6 | |1XQ3,1XQ2,1E3G,2ao6 | ||
Revision as of 06:48, 18 October 2008
| S.No | IDENTIFIER | NAME | PDB_ID | RECEPTOR | |
|---|---|---|---|---|---|
| 1 | R18 | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11- TRIEN-3-ONE | C19H24O2 | 1XQ3,1XQ2,1E3G,2ao6 | ANDROGEN |
| 2 | ZK5 | 9ALPHA-FLUOROCORTISOL | C21H29FO5 | 1GS4 | ANDROGEN |
| 3 | 17H | 17-HYDROXY-18A-HOMO-19-NOR-17ALPHA-PREGNA- 4,9,11-TRIEN-3-ONE | C21H28O2 | 2amb | ANDROGEN |
| 4 | TES | TESTOSTERONE | C19H28O2 | 2am9,2q7i,2q7k,2q7j | ANDROGEN |
| 5 | DHT | 5-ALPHA-DIHYDROTESTOSTERONE | C19H30O2 | 2ama,1i37,1i38,1t5z,1t63,1t65,1t73,1t74,1t75,1t76,1t79,1t7f,1t7m,1t7r,1t7t,1xj7,2piv,2piw,2pkl,2qpy,2z4j,2pio,2pip,2piq,2pir,2pit,2piu,2pix,1d2s | ANDROGEN |
| 6 | LG7 | 4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-1-NAPHTHONITRILE | C17H13N3O3 | 2ihq | ANDROGEN |
| 7 | HYQ | REL-(3AR,4S,7R,7AS)-3A,4,7,7A-TETRAHYDRO-2-(4-NITRO-1-NAPHTHALENYL)-4,7-ETHANO-1H-ISOINDOLE-1,3(2H)-DIONE | C20H18N2O4 | 1xnn | ANDROGEN |
| 8 | HFT | HYDROXYFLUTAMIDE | C11H11F3N2O4 | 2ax6 | ANDROGEN |
| 9 | 8NH | 2-CHLORO-4-[(7R,7AS)-7-HYDROXY-1,3-DIOXOTETRAHYDRO-1H-PYRROLO[1,2-C]IMIDAZOL-2(3H)-YL]-3-METHYLBENZONITRILE | C14H12ClN3O3 | 2nw4 | ANDROGEN |
| 10 | FHM | S-3-(4-FLUOROPHENOXY)-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE | C17H14F4N2O5 | 2ax7,2ax8,2axa | ANDROGEN |
| 11 | BHM | (R)-3-BROMO-2-HYDROXY-2-METHYL-N-[4-NITRO-3-(TRIFLUOROMETHYL)PHENYL]PROPANAMIDE | C11H10BrF3N2O4 | 2ax9 | ANDROGEN |
| 12 | I98 | R-BICALUTAMIDE | C18H14F4N2O4S | 1z95 | ANDROGEN |
| 13 | CA4 | CYPROTERONE ACETATE | C24H29ClO4 | 2oz7 | ANDROGEN |
| 14 | ENM | (5S,8R,9S,10S,13R,14S,17S)-13-{2-[(3,5-DIFLUOROBENZYL)OXY]ETHYL}-17-HYDROXY-10-METHYLHEXADECAHYDRO-3H-CYCLOPENTA[A]PHENANTHREN-3-ONE | C27H36F2O3 | 2pnu | ANDROGEN |
| 15 | LGD | 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE | C14H9F9N2O | 2hvc | ANDROGEN |
| 16 | B5R | (2S)-3-(4-chloro-3-fluorophenoxy)-N-[4-cyano- 3-(trifluoromethyl)phenyl]-2-hydroxy-2-methylpropanamide | C18H13ClF4N2O3 | 3b5r | ANDROGEN |
| 17 | 3B6 | (2S)-N-(4-cyano-3-iodophenyl)-3-(4-cyanophenoxy)- 2-hydroxy-2-methylpropanamide | C18H14IN3O3 | 3b65 | ANDROGEN |
| 18 | B66 | 4-{[(1R,2S)-1,2-dihydroxy-2-methyl-3-(4-nitrophenoxy)propyl]amino}-2-(trifluoromethyl)benzonitrile | C18H16F3N3O5 | 3b66 | ANDROGEN |
| 19 | B67 | (2S)-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]-3-(pentafluorophenoxy)propanamide | C17H10F8N2O5 | 3b67 | ANDROGEN |
| 20 | B68 | (2S)-3-[4-(acetylamino)phenoxy]-2-hydroxy-2-methyl-N-[4-nitro-3-(trifluoromethyl)phenyl]propanamide | C19H18F3N3O6 | 3b68 | ANDROGEN |
| 21 | AON | 5-ALPHA-ANDROSTANE-3-BETA,17-ALPHA-DIOL | C19H32O2 | 1lhn | ANDROGEN |
| 22 | AOM | 5-ALPHA-ANDROSTANE-3-BETA,17BETA-DIOL | C19H32O2 | 1lho | ANDROGEN |
| 23 | EST | ESTRADIOL | C18H24O2 | 1A52,1ERE,1G50,1GWR,1PCG,1QKT,1QKU,2OCF,2J7X | ESTROGEN |
| 24 | RAL | RALOXIFENE | C28H27NO4S | 1ERR,2JFA,1QK | ESTROGEN |
| 25 | ZTW | RALOXIFENE CORE | C14H10O2S | 1GWQ | ESTROGEN |
| 26 | ETC | (R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE- 2,8-DIOL | C22H24O2 | 1L2I,1L2J | ESTROGEN |
| 27 | GW5 | (2E)-3-{4-[(1E)-1,2-DIPHENYLBUT-1-ENYL]PHENYL}ACRYLIC ACID | C25H22O2 | 1R5K | ESTROGEN |
| 28 | E4D | (2S,3R)-2-(4-(2-(PIPERIDIN-1-YL)ETHOXY)PHENYL)-2,3-DIHYDRO-3-(4-HYDROXYPHENYL)BENZO[B][1,4]OXATHIIN-6-OL | C27H29NO4S | 1SJ0 | ESTROGEN |
| 29 | PTI | 2-PHENYL-1-[4-(2-PIPERIDIN-1-YL-ETHOXY)-PHENYL]-1,2,3,4-TETRAHYDRO-ISOQUINOLIN-6-OL | C28H32N2O2 | 1UOM | ESTROGEN |
| 30 | 244 | [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN- 7-YL]ACETONITRILE | C16H11NO3 | 1X7E | ESTROGEN |
| 31 | GEN | GENISTEIN | C15H10O5 | 1X7R,2QA8,1QKM,1X7J | ESTROGEN |
| 32 | AIH | (2S,3R)-2-(4-{2-[(3R,4R)-3,4-DIMETHYLPYRROLIDIN-1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL | C28H31NO4S | 1XP1 | ESTROGEN |
| 33 | AIU | (2S,3R)-2-(4-{2-[(3S,4S)-3,4-DIMETHYLPYRROLIDIN- 1-YL]ETHOXY}PHENYL)-3-(4-HYDROXYPHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL | C28H31NO4S | 1XP6 | ESTROGEN |
| 34 | AIJ | (2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2S)-2-PYRROLIDIN-1-YLPROPYL]OXY}PHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL | C27H29NO4S | 1XP9 | ESTROGEN |
| 35 | AIT | (2S,3R)-3-(4-HYDROXYPHENYL)-2-(4-{[(2R)-2-PYRROLIDIN-1-YLPROPYL]OXY}PHENYL)-2,3-DIHYDRO-1,4-BENZOXATHIIN-6-OL | C27H29NO4S | 1XPC | ESTROGEN |
| 36 | AEJ | (1S)-1-{4-[(9AR)-OCTAHYDRO-2H-PYRIDO[1,2-A]PYRAZIN-2-YL]PHENYL}-2-PHENYL-1,2,3,4-TETRAHYDROISOQUINOLIN-6-OL | C29H33N3O | 1XQC | ESTROGEN |
| 37 | CM4 | (2R,3R,4S)-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PYRROLIDIN-1YLETHOXY)PHENYL]CHROMAN-6-OL | C28H31NO4 | 1YIM | ESTROGEN |
| 38 | CM3 | (2R,3R,4S)-5-FLUORO-3-(4-HYDROXYPHENYL)-4-METHYL-2-[4-(2-PIPERIDIN-1-YLETHOXY)PHENYL]CHROMAN-6-OL | C29H32FNO4 | 1YIN | ESTROGEN |
| 39 | 689 | 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-6,8,9-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL | C18H24O3 | 1ZKY | ESTROGEN |
| 40 | L4G | 6-(4-METHYLSULFONYL-PHENYL)-5-[4-(2-PIPERIDIN- 1-YLETHOXY)PHENOXY]NAPHTHALEN-2-OL | C30H31NO5S | 2AYR | ESTROGEN |
| 41 | 458 | 4-[(1S,2S,5S)-5-(HYDROXYMETHYL)-8-METHYL- 3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL | C16H20O3 | 2BIV | ESTROGEN |
| 42 | 17M | 17-METHYL-17-ALPHA-DIHYDROEQUILENIN | C19H22O2 | 2B1Z | ESTROGEN |
| 43 | OHT | 4-HYDROXYTAMOXIFEN | C26H29NO2 | 2BJ4,2JF9,3ERT,2FSZ | ESTROGEN |
| 44 | 459 | 4-[(1S,2S,5S,9R)-5-(HYDROXYMETHYL)-8,9-DIMETHYL- 3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL | C17H24O3 | 2FAI | ESTROGEN |
| 45 | T3O | 4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON- 7-EN-2-YL]PHENOL | C17H22O2 | 2G44 | ESTROGEN |
| 46 | DRQ | (9ALPHA,13BETA,17BETA)-2-[(1Z)-BUT-1-EN-1- YL]ESTRA-1,3,5(10)-TRIENE-3,17-DIOL | C22H30O2 | 2G5O | ESTROGEN |
| 47 | I0G | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B- HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL | C18H18O3 | 2I0J,2I0G | ESTROGEN |
| 48 | IOG | N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]- 2-[2-PHENYL-6-(2-PIPERIDIN-1-YLETHOXY)-1H- INDOL-3-YL]ACETAMIDE | C33H39N3O3 | 2IOG | ESTROGEN |
| 49 | IOK | N-[(1R)-3-(4-HYDROXYPHENYL)-1-METHYLPROPYL]- 2-(2-PHENYL-1H-INDOL-3-YL)ACETAMIDE | C26H26N2O2 | 2IOK | ESTROGEN |
| 50 | C3D | (5R,6S)-6-PHENYL-5-[4-(2-PYRROLIDIN-1-YLETHOXY)PHENYL]- 5,6,7,8-TETRAHYDRONAPHTHALEN-2-OL | C28H31NO2 | 2OUZ | ESTROGEN |
| 51 | EZT | (17BETA)-17-{(E)-2-[2-(TRIFLUOROMETHYL)PHENYL]VINYL}ESTRA- 1(10),2,4-TRIENE-3,17-DIOL | C27H29F3O2 | 2P15 | ESTROGEN |
| 52 | WST | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B- HEXAHYDROCYCLOPENTA[C]CHROMEN-9-OL | C18H18O3 | 2POG | ESTROGEN |
| 53 | A48 | 4-[(DIMESITYLBORYL)(2,2,2-TRIFLUOROETHYL)AMINO]PHENOL | C26H29BF3NO | 2Q6J | ESTROGEN |
| 54 | DC8 | (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)- 1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN- 8-OL | C18H16F2O3 | 2Q70 | ESTROGEN |
| 55 | KN2 | 4-(6-HYDROXY-1H-INDAZOL-3-YL)BENZENE-1,3- DIOL | C13H10N2O3 | 2QA6 | ESTROGEN |
| 56 | EI1 | 3-ETHYL-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5- OL | C15H14N2O2 | 2QAB | ESTROGEN |
| 57 | JJ3 | (3AS,4R,9BR)-4-(4-HYDROXYPHENYL)-6-(METHOXYMETHYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL | C20H22O4 | 2QE4,2JJ3 | ESTROGEN |
| 58 | EED | (9BETA,11ALPHA,13ALPHA,14BETA,17ALPHA)-11-(METHOXYMETHYL)ESTRA-1(10),2,4-TRIENE-3,17-DIOL | C20H28O3 | 2QGT | ESTROGEN |
| 59 | EES | 3-CHLORO-2-(4-HYDROXYPHENYL)-2H-INDAZOL-5-OL | C13H9ClN2O2 | 2QGW | ESTROGEN |
| 60 | ODE | DIETHYL (1R,2S,3R,4S)-5,6-BIS(4-HYDROXYPHENYL)- 7-OXABICYCLO[2.2.1]HEPT-5-ENE-2,3-DICARBOXYLATE | C24H24O7 | 2QH6 | ESTROGEN |
| 61 | HZ3 | dimethyl (1R,4S)-5,6-bis(4-hydroxyphenyl)- 7-oxabicyclo[2.2.1]hepta-2,5-diene-2,3-dicarboxylate | C22H18O7 | 2QR9 | ESTROGEN |
| 62 | 1HP | 4-(2-amino-1-methyl-1H-imidazo[4,5-b]pyridin- 6-yl)phenol | C13H12O | 2QSE | ESTROGEN |
| 63 | PIQ | 2-AMINO-1-METHYL-6-PHENYLIMIDAZO[4,5-B]PYRIDINE | C13H12N4 | 2QXM | ESTROGEN |
| 64 | LLB | [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien- 3-yl]{4-[2-(4-methylpiperidin-1-yl)ethoxy]phenyl}methanone | C29H29NO4S | 2R6W | ESTROGEN |
| 64 | LLC | [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothien- 3-yl][4-(2-pyrrolidin-1-ylethoxy)phenyl]methanone | C27H25NO4S | 2R6Y | ESTROGEN |
| 66 | SAH | S-ADENOSYL-L-HOMOCYSTEINE | C14H20N6O5S | 3CMB | ESTROGEN |
| 67 | DES | DIETHYLSTILBESTROL | C18H20O2 | 3ERD | ESTROGEN |
| 68 | AOE | N-BUTYL-11-[(7R,8R,9S,13S,14S,17S)-3,17-DIHYDROXY-13-METHYL-7,8,9,11,12,13,14,15,16,17-DECAHYDRO-6H-CYCLOPENTA[A]PHENANTHREN-7-YL]-N-METHYLUNDECANAMIDE | C34H55NO3 | 1HJ1 | ESTROGEN |
| 69 | E3O | (16ALPHA,17ALPHA)-ESTRA-1,3,5(10)-TRIENE- 3,16,17-TRIOL | C18H24O3 | 2J7Y | ESTROGEN |
| 70 | MON | 4-(2-{[4-{[3-(4-CHLOROPHENYL)PROPYL]SULFANYL}- 6-(1-PIPERAZINYL)-1,3,5-TRIAZIN-2-YL]AMINO}ETHYL)PHENOL | C24H29ClN6OS | 1NDE | ESTROGEN |
| 71 | 272 | 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL | C13H9NO4 | 1U3Q | ESTROGEN |
| 72 | 338 | 2-(5-HYDROXY-NAPHTHALEN-1-YL)-1,3-BENZOOXAZOL-6-OL | C17H11NO3 | 1U3R | ESTROGEN |
| 73 | 797 | 3-(6-HYDROXY-NAPHTHALEN-2-YL)-BENZO[D]ISOOXAZOL-6-OL | C17H11NO3 | 1U3S | ESTROGEN |
| 74 | 397 | 2-(4-HYDROXY-PHENYL)BENZOFURAN-5-OL | C14H10O3 | 1U9E | ESTROGEN |
| 75 | 697 | 5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN- 7-CARBONITRILE | C15H9NO3 | 1X76 | ESTROGEN |
| 76 | 244 | [5-HYDROXY-2-(4-HYDROXYPHENYL)-1-BENZOFURAN-7-YL]ACETONITRILE | C16H11NO3 | 1X78 | ESTROGEN |
| 77 | 41 | 2-(3-FLUORO-4-HYDROXYPHENYL)-7-VINYL-1,3- BENZOXAZOL-5-OL | C15H10FNO3 | 1X7B | ESTROGEN |
| 78 | 4NA | 1-CHLORO-6-(4-HYDROXYPHENYL)-2-NAPHTHOL | C16H11ClO2 | 1YY4 | ESTROGEN |
| 79 | 196 | 3-(3-FLUORO-4-HYDROXYPHENYL)-7-HYDROXY-1- NAPHTHONITRILE | C17H10FNO2 | 1YYE | ESTROGEN |
| 80 | 789 | 3-BROMO-6-HYDROXY-2-(4-HYDROXYPHENYL)-1H- INDEN-1-ONE | C15H9BrO3 | 1ZAF | ESTROGEN |
| 81 | FBR | (9aS)-4-bromo-9a-butyl-7-hydroxy-1,2,9,9a- tetrahydro-3H-fluoren-3-one | C17H19Br | 2GIU | ESTROGEN |
| 82 | 555 | 4-(4-HYDROXYPHENYL)-1-NAPHTHALDEHYDE OXIME | C17H13NO2 | 2NV7 | ESTROGEN |
| 83 | DC8 | (3AS,4R,9BR)-2,2-DIFLUORO-4-(4-HYDROXYPHENYL)-1,2,3,3A,4,9B-HEXAHYDROCYCLOPENTA[C]CHROMEN-8-OL | C18H16F2O3 | 2Z4B | ESTROGEN |
