PolysacDB Lipopolysaccharide 1478

From DrugPedia: A Wikipedia for Drug discovery

Revision as of 06:08, 8 April 2010 (edit) Raghavagps (Talk | contribs) m (1 revision) ← Previous diff

Current revision (05:50, 9 September 2010) (edit) (undo) Raghavagps (Talk | contribs) m (1 revision)

---

Current revision

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Helicobacter pylori

[edit] Basic Structure

The structure of the O-polysaccharide part of the LPS is the same as the Lewis X (Lex) and Lewis Y (Ley) determinants of the human cell surface glycoconjugates

[edit] Proposed functions

The O-polysaccharide regions of these LPS were found to be a major antigenic determinant

[edit] Antigenic Nature used to produce antibodies

N/A

[edit] Carrier Name

N/A

[edit] Conjugation Method

N/A

[edit] Antibodies

Mab BG-6 (T218)

[edit] Antibody type and class

IgM

[edit] Assay System

Immunoblotting and ELISA

[edit] Cross-reactivity

This anti-Lex Mab reacted with strains CG4 and CA2, CG9 and GU10 and did not react with strains 43504-r and CG7

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

N/A

[edit] Weblink

PubMed Central

[edit] External Links

• BCSDB Structural Detail

• IEDB Epitopic Detail

• Link to PolysacDB database