Dr. G. P. S. Raghava

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{{Infobox Scientist  
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{{Infobox Scientist}}
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|name = Dr. G. P. S. Raghava
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|image = Raghava.jpg
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|image_size = 200px
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|caption = Dr. G.P.S. Raghava
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|birth_place = [[Uttar Pradesh]], [[India]]
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'''Gajendra Pal Singh Raghava (G.P.S. Raghava)''' is a scientist and head of Bioinformatics center, Institute of Microbial Technology ([[IMTECH]]), Chandigarh, India (For detail visit his [http://www.imtech.res.in/raghava/ Home Page]). 
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|residence =  [[India]]
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|nationality = [[India]]n
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|field = [[Bioinformatics]]
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|work_institution = [[Institute of Microbial Technology]]</br>[[Bioinformatics Center]]
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|doctoral_advisor =
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|doctoral_students =
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|religion = Hindu
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}}
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'''Dr. G P S Raghava''' is scientist and head of Bioinformatics center, Institute of Microbial Technology, Chandigarh, India (For detail Visit his [http://www.imtech.res.in/raghava/ home page].   
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== Personal ==
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===Early years and Education===
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Raghava was born on 25th May 1963 in village Nagla Karan, Buland Shahr (UP), India.  He did his M.Sc in Physics with specialization in electronics from N.A.S. College, Meerut, UP in 1984.  He did his M.Tech from Indian Institute of Technology (I.I.T.), New Delhi  in 1986. In 1996 he received his Doctrate degree from Institute of Microbial Technology and Panjab University, Chandigarh in area of  Bioinformatics. His PhD work focuses on "Computer Aided  Prediction of Protein Conformation from Amino Acid Sequences of  Biotechnological Relevance" .
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==Biography==
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===Carrier and Higher Studies===
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===Early years and education===
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He joined Institute of Microbial Technology, Chandigarh in 1986 as computer scientist. His primary duty was to develop/maintain computer software/hardware and IT infrastructure. He become head of bioinformatics center in 1994. He is also coordinator of distributed information centre (DIC) supported by DBT under BTISNET programme, where his primary duty is to built/maintain infrastructure required for protein modeling and engineering.  
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G P S Raghava was born on ---- 19-- in Uttar Pradesh in nothern India.  
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Raghava completed his primary education from his native place (Vill. Nagla Karan, Dist. Bulandshahr, Uttar Pradesh, India). He did his High School from Utravali-Mankpur in  1978 and Intermediate from Lakhoti in 1980. He did his Bachelors of science from N.A.S. College, Meerut, UP in 1982.  His major subjects were Physics,  Chemistry and Mathematics. He did his Masters of Science from N.A.S. College, Meerut, UP in 1984 with physics as majors and  did specilisation in Electronics. Then Raghava did his M.Tech from Indian Institute of Technology (I.I.T.), New Delhi  in 1986 with main subjects as Computer Applications, Microprocessor  based systems and Computer Hardware/ software under the Energy  studies. In 1996 he received his Doctrate degree from Institute of Microbial Technology  and Panjab University, Chandigarh in area of  Bioinformatics. His PhD work focuses on "Computer Aided  Prediction of Protein Conformation from Amino Acid Sequences of  Biotechnological Relevance" . He worked as a  Post Doctrate Fellow (PDF) at Oxford university as well as at European Bioinformatics Institute (EBI) Cambridge, United Kingdom  for two years (1996-98). During this period he developed number of  web servers in area of computational biology particularly in Protein  Modelling.  
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He worked as a  Post Doctrate Fellow (PDF) at Oxford university as well as at European Bioinformatics Institute (EBI) Cambridge, United Kingdom  for two years (1996-98). During this period he learned and developed number of  web servers in area of computational biology particularly in Protein  Modelling.  
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He joined IMTECH in 1986. His primary duty was to develop computer software, to maintain computer hardware/software and to maintain network at IMTECH. He become head of bioinformatics center in 19--. He is also looking after distributed information centre (DIC) supported by DBT under BTISNET programme, where his primary duty is to built/maintain infrastructure required for protein modeling and engineering.  He is developing software in the field of bioscience since 1990.
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===Achievements and Awards===
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*Raghava got prestigious Shanti Swarup Bhatnagar Prize for Science and Technology for 2008 (http://www.hindu.com/2008/09/28/stories/2008092859630900.htm)
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===IT Related Services===
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*Raghava got National Bioscience Award of year 2005-6 for carrier development of Department of Biotechnology (Govt. of India) New Delhi  
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*Creation of new biological databases and to maintain local mirror of popular databases
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*Maintain email, local area network and internet facilities at IMTECH
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*Built and maintain infrastructure required to full fill IT (Information Technology) needs of IMTECH.
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===Research and Development===
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*Develop better methods for predicting structure of proteins from its primary structure particularly irregular secondary structure (e.g. Tight Turns)
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*Annotation of genomes and comparative genomics particularly gene/repeat prediction
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*Functional annotation and classification of proteins (e.g. Subcellular localization of proteins, classification of NR and GPCR)
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*Identification of subunit vaccine candidates by developing better methods for epitope prediction (adaptive immunity) and adjutants  (innate immunity)
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*Participate in international competitions likes CASP, CAFASP and EVA
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===Acheivements===
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*Dr Raghava has published more than 90 research papers in reputed journals, developed 7 currated databases and more than 80 web servers, and 30 copyrights.
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*Research fellowship (1984-86) was awarded by IIT Delhi, after qualifying national test GATE.
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*BBSRC fellowship, funded by UK for postdoctoral studies at Oxford University, UK from 1996 to 1998. During this period I developed a number of web servers in the area of computational biology particularly in Protein Modelling.
*BBSRC fellowship, funded by UK for postdoctoral studies at Oxford University, UK from 1996 to 1998. During this period I developed a number of web servers in the area of computational biology particularly in Protein Modelling.
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*Invited by University of Arkansas for Medical Sciences (UAMS), Little Rock, USA to establish Bioinformatics (http://bioinformatics.uams.edu/)
 
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*Methods developed at group successfully participate and ranked in top methods in the world in international competitions like CASP, CAFASP and EVA. Protein secondary structure prediction server is always in  top 5 servers in the world.
 
*Government of Korea offered Visiting Professorship for six months (March 2004 to August 2004) to initiate Bioinformatics activities at Pohang University of Science and Technolgy (POSTECH).
*Government of Korea offered Visiting Professorship for six months (March 2004 to August 2004) to initiate Bioinformatics activities at Pohang University of Science and Technolgy (POSTECH).
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*Two curated databases (MHBN: MHC binders/non-bindedrs & BCIpep: B-Cell epitopes) have been developed by our group are distributed by  European Bioinformatics Institute, UK (EBI).
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*Invited by University of Arkansas for Medical Sciences (UAMS), Little Rock, USA to establish Bioinformatics (http://bioinformatics.uams.edu/)
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*Raghava was a key figure in the development  of BioSuite which is a bioinformatics software developed by TCS with experts in bioinformatics under NMITLI programmee. This package has been launched by HonÕble President of India Dr APJ Abdul Kalam, on 14th July 2004.
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*Dr Raghava has published more than 90 research papers in reputed journals, developed 7 currated databases and more than 80 web servers, and 30 copyrights.
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*In collaboration with private company Biomantra. We (Biomantra and IMTECH) developed a software package ÒVaxiPred: Computer aided vaccine designÓ, based on research carried out at my group. This package has been launched by Director General, CSIR Dr R A Mashlekar on 15th of December 2004.
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*Raghava was a key figure in the development  of BioSuite software developed by TCS under NMITLI programmee, which was launched by Honable President of India Dr APJ Abdul Kalam, on 14th July 2004.
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*Reviewed more than 50 papers for reputed journals like NAR, Bioinformatics, proteins etc.
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*His group in collaboration with private company Biomantra developed a software package VaxiPred: Computer aided vaccine design, which was launched by Director General, CSIR Dr R A Mashlekar on 15th of December 2004.
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*Invited to revive papers submitted to ISMB 2005 and PSB 2006, projects submitted for grants etc.
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=== Awards ===
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*Dr Raghava got National Bioscience Award of year 2005-6 for carrier development of Department of Biotechnology (Govt. of India) New Delhi
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===Distinguished Positions===
===Distinguished Positions===
*He was elected as Fellow of National Academy of Sciences by "The National Academy of Sciences, India" for his excellent contribution in the field of Bioinformatics.
*He was elected as Fellow of National Academy of Sciences by "The National Academy of Sciences, India" for his excellent contribution in the field of Bioinformatics.
*Dr. Raghava is listed as a hot 100 authors by BioMed Central for his contributions
*Dr. Raghava is listed as a hot 100 authors by BioMed Central for his contributions
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*Dr Raghava has H-index 22 in May 2008 as per google scolar . H-index is used to measure performance of a researcher.
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*Dr Raghava has H-index 22 in May 2008 as per google scolar. H-index is used to measure performance of a researcher.
*Associate Editor of BMC Research Notes.
*Associate Editor of BMC Research Notes.
*Member of Editorial Board of Journal of Biomedical Science and Engineering.
*Member of Editorial Board of Journal of Biomedical Science and Engineering.
*Associate Editor of Journal of Applied Sciences.
*Associate Editor of Journal of Applied Sciences.
*Member of Editorial Advisory Board of journal Recent Patents on DNA & Gene Sequences
*Member of Editorial Advisory Board of journal Recent Patents on DNA & Gene Sequences
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== Research Interests ==
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Accidently in 1991, he got interest in research and developed a method for calculating concentration of Antibody/Antigen from ELISA data. In initial phase he developed computer programs for general biological problems. In later stage he developed prediction method for protein secondary structure prediction; his methods successfully compete in international competitions like [[casp]]. In 1999 he establish his research group at IMTECH with emphasis on proteins structure prediction and genome annotation. In 2001, his group also focussed on "Computer aided vaccine design" with emphasis on subunit vaccine design. Since 2006, his group is trying to integrate bioinformatics, chemoinformatics, pharmacoinformatics, clinical informatics in order to develop single plate form for designing drugs in insilico.
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== Web Services and Software ==
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He believes in public domain software or open source software/documents. Thus his group is using free software and building infrastructure for bioinformatics. All software and web servers developed at his group are free for academic use. Recently his group have initiated a web portal [http://crdd.osdd.net/ CRDD: Computational Resources for Drug Discovery] under [http://www.osdd.org/ OSDD]. Services provided from his group can be broadly classified in following categories.
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===Computer-aided Protein Structure Prediction===
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{| border="1"  align="center"
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|+'''Table I'''
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|+''' Computer-aided Protein Structure Prediction softwares'''
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/apssp2/ APSSP2]
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/proclass/ PROCLASS]
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/psa/ PSA]
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/rpfold/ RPFOLD]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/bteval/ BTEVAL]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/betatpred2/ BetatPred2]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/betatpred/ BetatPred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/chpredict/ CHpredict]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/ar_nhpred/ AR_NHPred]
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/tbbpred/ TBBPred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/betaturns/ BetaTurns]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/bhairpred/ BhairPred]||style="background:beige;text-align:center"|[http://www.compbio.dundee.ac.uk/Software/Oxbench/oxbench.html OXBench]||style="background:beige"|[http://www.imtech.res.in/raghava/strucomp/ StruComp]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/gammapred/ GammaPred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/alphapred/ AlphaPred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/pepstr/ PepStr]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/sarpred/ SarPred]
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|-
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|}
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===Immunoinformatics: Subunit Vaccine design===
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{| border="1" align="center"
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|+'''Table II'''
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|+''' Immunoinformatics softwares'''
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/propred1/ PROPRED1]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/nhlapred/ nHLApred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/mmbpred/ MMBpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/pcleavage/ Pcleavage]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/tappred/ TAPpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/ctlpred/ CTLpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/propred/ PROPRED]
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/hladr4pred/ HLADR4pred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/mhc2pred/ MHC2pred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/mhc/ MHC]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/mhcbench/ MHCbench]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/abag/ AbAg]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/bcepred/ BCEpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/abcpred/ ABCpred]
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/bcipep/ BCIPep]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/hlapred/ HLApred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/mhcbn/  MHCBN]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/haptendb/ HaptenDB]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/hla_affi/ HLA_affi]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/fdr4/ FDR4]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/tmhcpred/ Tmhcpred]
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|-
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|}
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===Genome Annotation===
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{| border="1" align="center"
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|+'''Table III'''
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|+''' Genome Annotation softwares'''
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/ftg/ FTG]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/gwblast/ GWBLAST]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/gwfasta/ GWFASTA]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/egpred/ EGPred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/svmgene/ SVMgene]
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/srf/ SRF]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/MyPattern/ MyPattern]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/genebench/ GeneBench]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/ftgpred/ FTGPred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/cdpred/ CDpred]
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/dnabinder/ DNAbinder]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/polyapred/ Polyapred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/pprint/ Pprint]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/ecgpred/ ECGpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/sgpred/ SGpred]
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|-
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|}
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===Functional Annotation of Proteins===
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{| border="1" align="center"
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|+'''Table IV'''
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|+''' Functional Annotation softwares'''
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|-
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|style="background:beige;text-align:center"|AC2Dgel||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/nrpred/ NRpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/gpcrpred/ GPCRpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/gpcrsclass/ GPCRsclass]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/eslpred/ ESLpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/pslpred/ PSLpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/btxpred/ BTXpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/mitpred/ Mitpred]
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/srtpred/ SRTpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/oxypred/ Oxypred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/vgichan/ VGIchan]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/hslpred/ HSLpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/dnasize/ DNAsize]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/gstpred/ GSTpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/mango/ Mango]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/lgepred/ LGEpred]
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/ntxpred/ NTXpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/vicmpred/ VICMpred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/algpred/ AlgPred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/pseapred/ PseaPred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/rslpred/ RSL-Pred]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/antibp/ AntiBP]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/copid/ COPid]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/sirnapred/ siRNAPred]
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/isspred/ ISSPred]
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|-
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|}
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===Chemoinformatics and Pharmacoinformatics===
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{| border="1" align="center"
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|+'''Table V'''
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|+''' Chemoinformatics and Pharmacoinformatics softwares'''
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/dadpred/ DADPRED]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/dmkpred/ DMKPred]||style="background:beige;text-align:center"|[http://172.141.127.22/raghava/kidoq/ KiDoQ]
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|-
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|}
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== Databases ==
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{| border="1" align="center"
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|+''' List of Databases developed'''
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|-
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|style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/mhcbn/ MHCBN]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/bcipep/ BCIPEP]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/haptendb/ HaptenDB]||style="background:beige;text-align:center"|[http://www.imtech.res.in/rfsb/ RFSB]||style="background:beige;text-align:center"|[http://www.imtech.res.in/fsgp/ FSGP]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/prrdb/ PRRDB]||style="background:beige;text-align:center"|[http://www.imtech.res.in/raghava/antigendb/ AntigenDB]
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|-
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|}
==External links==
==External links==
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* [http://www.imtech.res.in/raghava/about.html]
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*[http://www.imtech.res.in/raghava/ Raghava Home]
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*[http://www.biolicious.com/rankings.php Ranking of Bioinformaticians]

Current revision

Dr. G. P. S. Raghava Birth_place Uttar Pradesh, India Residence India Nationality Indian Field Bioinformatics Work_Institution Institute of Microbial Technology Bioinformatics Center Religion Hindu
Dr. G. P. S. Raghava Birth_place Uttar Pradesh, India
Residence India Nationality Indian Field Bioinformatics Work_Institution Institute of Microbial Technology Bioinformatics Center Religion Hindu

Gajendra Pal Singh Raghava (G.P.S. Raghava) is a scientist and head of Bioinformatics center, Institute of Microbial Technology (IMTECH), Chandigarh, India (For detail visit his Home Page).

Contents

[edit] Personal

[edit] Early years and Education

Raghava was born on 25th May 1963 in village Nagla Karan, Buland Shahr (UP), India. He did his M.Sc in Physics with specialization in electronics from N.A.S. College, Meerut, UP in 1984. He did his M.Tech from Indian Institute of Technology (I.I.T.), New Delhi in 1986. In 1996 he received his Doctrate degree from Institute of Microbial Technology and Panjab University, Chandigarh in area of Bioinformatics. His PhD work focuses on "Computer Aided Prediction of Protein Conformation from Amino Acid Sequences of Biotechnological Relevance" .

[edit] Carrier and Higher Studies

He joined Institute of Microbial Technology, Chandigarh in 1986 as computer scientist. His primary duty was to develop/maintain computer software/hardware and IT infrastructure. He become head of bioinformatics center in 1994. He is also coordinator of distributed information centre (DIC) supported by DBT under BTISNET programme, where his primary duty is to built/maintain infrastructure required for protein modeling and engineering.

He worked as a Post Doctrate Fellow (PDF) at Oxford university as well as at European Bioinformatics Institute (EBI) Cambridge, United Kingdom for two years (1996-98). During this period he learned and developed number of web servers in area of computational biology particularly in Protein Modelling.

[edit] Achievements and Awards

  • Raghava got prestigious Shanti Swarup Bhatnagar Prize for Science and Technology for 2008 (http://www.hindu.com/2008/09/28/stories/2008092859630900.htm)
  • Raghava got National Bioscience Award of year 2005-6 for carrier development of Department of Biotechnology (Govt. of India) New Delhi
  • BBSRC fellowship, funded by UK for postdoctoral studies at Oxford University, UK from 1996 to 1998. During this period I developed a number of web servers in the area of computational biology particularly in Protein Modelling.
  • Government of Korea offered Visiting Professorship for six months (March 2004 to August 2004) to initiate Bioinformatics activities at Pohang University of Science and Technolgy (POSTECH).
  • Invited by University of Arkansas for Medical Sciences (UAMS), Little Rock, USA to establish Bioinformatics (http://bioinformatics.uams.edu/)
  • Dr Raghava has published more than 90 research papers in reputed journals, developed 7 currated databases and more than 80 web servers, and 30 copyrights.
  • Raghava was a key figure in the development of BioSuite software developed by TCS under NMITLI programmee, which was launched by Honable President of India Dr APJ Abdul Kalam, on 14th July 2004.
  • His group in collaboration with private company Biomantra developed a software package VaxiPred: Computer aided vaccine design, which was launched by Director General, CSIR Dr R A Mashlekar on 15th of December 2004.

[edit] Distinguished Positions

  • He was elected as Fellow of National Academy of Sciences by "The National Academy of Sciences, India" for his excellent contribution in the field of Bioinformatics.
  • Dr. Raghava is listed as a hot 100 authors by BioMed Central for his contributions
  • Dr Raghava has H-index 22 in May 2008 as per google scolar. H-index is used to measure performance of a researcher.
  • Associate Editor of BMC Research Notes.
  • Member of Editorial Board of Journal of Biomedical Science and Engineering.
  • Associate Editor of Journal of Applied Sciences.
  • Member of Editorial Advisory Board of journal Recent Patents on DNA & Gene Sequences

[edit] Research Interests

Accidently in 1991, he got interest in research and developed a method for calculating concentration of Antibody/Antigen from ELISA data. In initial phase he developed computer programs for general biological problems. In later stage he developed prediction method for protein secondary structure prediction; his methods successfully compete in international competitions like casp. In 1999 he establish his research group at IMTECH with emphasis on proteins structure prediction and genome annotation. In 2001, his group also focussed on "Computer aided vaccine design" with emphasis on subunit vaccine design. Since 2006, his group is trying to integrate bioinformatics, chemoinformatics, pharmacoinformatics, clinical informatics in order to develop single plate form for designing drugs in insilico.

[edit] Web Services and Software

He believes in public domain software or open source software/documents. Thus his group is using free software and building infrastructure for bioinformatics. All software and web servers developed at his group are free for academic use. Recently his group have initiated a web portal CRDD: Computational Resources for Drug Discovery under OSDD. Services provided from his group can be broadly classified in following categories.


[edit] Computer-aided Protein Structure Prediction

Table I Computer-aided Protein Structure Prediction softwares
APSSP2 PROCLASS PSA RPFOLDBTEVALBetatPred2BetatPredCHpredictAR_NHPred
TBBPredBetaTurnsBhairPredOXBenchStruCompGammaPredAlphaPredPepStrSarPred


[edit] Immunoinformatics: Subunit Vaccine design

Table II Immunoinformatics softwares
PROPRED1nHLApredMMBpredPcleavageTAPpredCTLpredPROPRED
HLADR4predMHC2predMHCMHCbenchAbAgBCEpredABCpred
BCIPepHLApredMHCBNHaptenDBHLA_affiFDR4Tmhcpred


[edit] Genome Annotation

Table III Genome Annotation softwares
FTGGWBLASTGWFASTAEGPredSVMgene
SRFMyPatternGeneBenchFTGPredCDpred
DNAbinderPolyapredPprintECGpredSGpred


[edit] Functional Annotation of Proteins

Table IV Functional Annotation softwares
AC2DgelNRpredGPCRpredGPCRsclassESLpredPSLpredBTXpredMitpred
SRTpredOxypredVGIchanHSLpredDNAsizeGSTpredMangoLGEpred
NTXpredVICMpredAlgPredPseaPredRSL-PredAntiBPCOPidsiRNAPred ISSPred


[edit] Chemoinformatics and Pharmacoinformatics

Table V Chemoinformatics and Pharmacoinformatics softwares
DADPREDDMKPredKiDoQ

[edit] Databases

List of Databases developed
MHCBNBCIPEPHaptenDBRFSBFSGPPRRDBAntigenDB

[edit] External links