PolysacDB O-polysaccharide 1261

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Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

O-polysaccharide

[edit] Carbohydrate Class

O-polysaccharide [LPS]

[edit] Source Microbe

Campylobacter fetus 554

[edit] Basic Structure

The LPS molecule of C. fetus is composed of three distinct structural domains: a hydrophobic lipid A portion which forms the outer leaflet of the outer membrane and which contains the endotoxic activity, a low-molecular-weight oligosaccharide core complex, and a variable-length O-specific polysaccharide chain with repeating oligosaccharide units (O-antigen)

[edit] Proposed functions

The LPS O-antigens are the basis of the C. fetus heat-stable serotyping Scheme

[edit] Antigenic Nature used to produce antibodies

a mixture (1:1) of C. fetus 553 and 554 formalin-killed cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab M1183

[edit] Antibody type and class

IgG1

[edit] Assay System

Indirect ELISA, immunoblotting,

[edit] Cross-reactivity

This antibody was specific to O antigen of C. fetus 553 and did not cross-react with C. fetus 554

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab can be used to serotype C. fetus strains

[edit] Weblink

PubMed Central

[edit] External Links

• Link to PolysacDB database