CarboDB Vi antigen 2175
From DrugPedia: A Wikipedia for Drug discovery
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[edit] Carbohydrate Name
Vi antigen
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Salmonella typhi 620Ty
[edit] Basic Structure
Vi antigen is a linear homopolymer of 1-->4(2-deoxy-2-N-acetylgalacturonic acid)
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Purified Vi antigen
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab Vi4a
[edit] Antibody type and class
IgG2b
[edit] Assay System
passive hemagglutination (PHA) and enzyme-linked immunosorbent assay (ELISA), Whole-cell radioimmunoassay, dot radioimmunoassay
[edit] Cross-reactivity
This Mab recognized the Vi antigen in Citrobacter strain 5396/38 and also reacted with the Vi antigens in S. typhi and S. dublin strains
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
The Vi-agglutiniating ability of the Mab might have application in the identification of S. typhi