CarboDB Capsular polysaccharide 1463
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
m (1 revision) |
Current revision
[edit] Carbohydrate Name
Capsular polysaccharide
[edit] Carbohydrate Class
Capsular polysaccharide
[edit] Source Microbe
Enterococcus faecalis
[edit] Basic Structure
Glycerol teichoic acid-like molecules with a carbohydrate backbone structure of 6-α-D-glucose- 1-->2 glycerol-3-PO4 with substitution on carbon 2 of the glucose with an α-2-1-D-glucose residue
[edit] Proposed functions
These polysaccharides are major virulence factors
[edit] Antigenic Nature used to produce antibodies
nil
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Healthy human sera
[edit] Antibody type and class
IgG and IgM
[edit] Assay System
ELISA
[edit] Cross-reactivity
The antisera bound to all 4 serotypes of E. fecalis CPS-A to CPS-D
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
These antibodies promote neutrophil mediated killing