CarboDB Lipopolysaccharide 1049

From DrugPedia: A Wikipedia for Drug discovery

(Difference between revisions)
Jump to: navigation, search
m (1 revision)

Revision as of 06:02, 8 April 2010


Contents

Carbohydrate Name

Lipopolysaccharide

Carbohydrate Class

Lipopolysaccharide

Source Microbe

Escherichia coli strain J5 (chemotype Rc)

Basic Structure

The core oligosaccharide part of the LPS consists of the following residues : α-D-Glcp(1-->2)α-D-Glcp(1-->2)α-D-Glcp [branched to α-D-GlcpNAc(1-->3)] (1-->3)α-L-D-man-Hepp [branched to α-D-GlcpNAc(1-->7)α-L-D-man-Hepp(1-->7)] and [branched to a phosphate group] (1-->3)α-L-D-man-Hepp [branched to α-Kdop(2-->4)α-Kdop(2-->4)α-Kdop(2-6)Subst] and [branched to a phosphate group](1-->5)


Proposed functions

N/A

Antigenic Nature used to produce antibodies

Whole cells

Carrier Name

nil

Conjugation Method

nil

Antibodies

Mab 2

Antibody type and class

IgG1

Assay System

ELISA, Limulus assay, invivo protection assay

Cross-reactivity

This antibody ross-reacted with Salmonella minnesota strain R5

Proposed epitopes

Terminal glucose residues

Proposed Utility

N/A

Weblink

[http://www.ncbi.nlm.nih.gov/pubmed/2455054 ?dopt=Abstract' PubMed]

External Links