Rv2121c
From DrugPedia: A Wikipedia for Drug discovery
(New page: {{immunebox | Name =<b> ATP phosphoribosyltransferase (hisG) </b> |image= | width=250 |image2= |Swiss Prot = P60759 | Genbank = 888689 | PDB = 1NH7 | Dr...) |
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Other PDBID: 1NH8 | Other PDBID: 1NH8 | ||
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Essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003) mutants available at TARGET website | Essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003) mutants available at TARGET website | ||
==Protein Sequence== | ==Protein Sequence== | ||
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TLSQHDLVAFGEPLCDSEAVLIERAGTDGQDQTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIA | TLSQHDLVAFGEPLCDSEAVLIERAGTDGQDQTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIA | ||
PLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF | PLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF | ||
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=Human Homologue Blast Result= | =Human Homologue Blast Result= | ||
Current revision
| Rv2121c
| |
| Name | |
| ATP phosphoribosyltransferase (hisG) | |
| Identifiers | |
| Swiss Prot | |
| Genbank | |
| PDB | |
| Chemical data | |
| Formula | C12H9BrO5 [1] |
| Mol. wt. | 30482 Da |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Solubility | ? |
| Isoelectric-Point | 4.7128 |
Contents |
[edit] General
THOUGHT TO BE INVOLVED IN HISTIDINE BIOSYNTHESIS.
Product: Probable ATP phosphoribosyltransferase HisG
Other PDBID: 1NH8
Essential gene by Himar1-based transposon mutagenesis in H37Rv strain (see Sassetti et al., 2003) mutants available at TARGET website
[edit] Protein Sequence
>Rv2121c, TB.seq 2379807:2380658 MW:30482 MLRVAVPNKGALSEPATEILAEAGYRRRTDSKDLTVIDPVNNVEFFFLRPKDIAIYVGSGELDFGITGRDLVCDSGAQVR ERLALGFGSSSFRYAAPAGRNWTTADLAGMRIATAYPNLVRKDLATKGIEATVIRLDGAVEISVQLGVADAIADVVGSGR TLSQHDLVAFGEPLCDSEAVLIERAGTDGQDQTEARDQLVARVQGVVFGQQYLMLDYDCPRSALKKATAITPGLESPTIA PLADPDWVAIRALVPRRDVNGIMDELAAIGAKAILASDIRFCRF
[edit] Human Homologue Blast Result
| subject ids | % identity | % positives | alignment length | evalue |
| sp|Q16836.2 | 23 | 50 | 69 | 4.1 |
| sp|O14531.2 | 31 | 43 | 90 | 4.3 |
[edit] Alergen Protein
Link to Algpred
Non Allergen Predicted by AlgPred Server
[edit] Bacterial Toxin Prediction
Link to btxpred
No Hit Fountd by btxpred server.
[edit] Subcellular Location
Link to TBpred
Cytoplasmic
[edit] Antigens
No Hit Found in AntigenDB
No. Hit Found in IEDB
[edit] B cell Epitopes
[edit] BCEpred Analysis
Link to Bcepred
Result Predicited by [2]
[edit] ABCpred Analysis
Link to ABCpred
Result Predicited by [3]
[edit] IEDB Analysis
Link to IEDB
Result Predicited by [4]
[edit] MHC Class-I Binder
[edit] nHLAPred Analysis
Link to nHLApred
Result Predicited by [5]
[edit] IEDB Analysis
Link to IEDB
Result Predicted by [6]
[edit] MHC Class-II Binder
[edit] Propred Analysis
Link to Propred
Result Predicted by [7]
[edit] NetMHC-II Analysis
Link to NetMHC-II
Result Predicted by [8]
[edit] External Links
- Database of Mycobacterium tuberculosis genome sequences and related information.
