Target Identification
From DrugPedia: A Wikipedia for Drug discovery
(→Target Identifiaction) |
(→Target Identifiaction) |
||
| Line 3: | Line 3: | ||
#Established Target | #Established Target | ||
#New Target | #New Target | ||
| - | Established Target molecule are those for which there is good scientific understanding and have history of both how the target functions in normal physiology and how it is involved in human pathology. The more such information is available, the less investment is (generally) required to develop a therapeutic directed against the target. | + | '''Established Target''' molecule are those for which there is good scientific understanding and have history of both how the target functions in normal physiology and how it is involved in human pathology. The more such information is available, the less investment is (generally) required to develop a therapeutic directed against the target. |
| - | New Target are all those targets that are not "established targets" but which have been or are the subject of drug discovery campaigns. These typically include newly discovered proteins, or proteins whose function has now become clear as a result of basic scientific research. | + | |
| + | '''New Target''' are all those targets that are not "established targets" but which have been or are the subject of drug discovery campaigns. These typically include newly discovered proteins, or proteins whose function has now become clear as a result of basic scientific research. | ||
===Disease Mechanism=== | ===Disease Mechanism=== | ||
Revision as of 15:02, 4 August 2008
Contents |
Target Identifiaction
Target identification is the phenomenon of identifying the molecule where a drug molecule can bind.eg. enzyme etc.Generallythe target molecule is can be two types.
- Established Target
- New Target
Established Target molecule are those for which there is good scientific understanding and have history of both how the target functions in normal physiology and how it is involved in human pathology. The more such information is available, the less investment is (generally) required to develop a therapeutic directed against the target.
New Target are all those targets that are not "established targets" but which have been or are the subject of drug discovery campaigns. These typically include newly discovered proteins, or proteins whose function has now become clear as a result of basic scientific research.
