Obestatin
From DrugPedia: A Wikipedia for Drug discovery
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==Description== | ==Description== | ||
Appetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Contains: Ghrelin; Obestatin]. | Appetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Contains: Ghrelin; Obestatin]. | ||
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403587 | 403587 | ||
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Current revision
Contents |
[edit] Description
Appetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Contains: Ghrelin; Obestatin].
[edit] Source Organism
Canis familiaris (Dog).
[edit] Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
[edit] Subcellular Localization
Secreted protein.
[edit] Developmental Stage
[edit] Similarity
Belongs to the motilin family.
[edit] Post translational Modification
O-n-octanoylation is essential for ghrelin activity (By similarity). Amidation of Leu-98 is essential for obestatin activity (By similarity).
[edit] Function
Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility
[edit] GeneID
403587
