Oxoglaucine
From DrugPedia: A Wikipedia for Drug discovery
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[http://crdd.osdd.net/raghava/biadb/detail.php?id=2132 Link to BIAdb Database] | [http://crdd.osdd.net/raghava/biadb/detail.php?id=2132 Link to BIAdb Database] | ||
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Current revision
| Oxoglaucine
| |
| Systematic (IUPAC) name | |
| N/A | |
| Identifiers | |
| CAS number | ? |
| ATC code | ? |
| PubChem | |
| ChemSpider | |
| Chemical data | |
| Formula | C20H17NO5 |
| Mol. mass | 351.35268 |
| SMILES | & |
| Pharmacokinetic data | |
| Bioavailability | ? |
| Metabolism | ? |
| Half life | ? |
| Excretion | ? |
| Therapeutic considerations | |
| Pregnancy cat. |
? |
| Legal status | |
| Routes | ? |
[edit] Description
oxoglaucine have been isolated from Annona cherimola 17 and from Croton hemiargyreus 89 respectively.the low doses (1 or 2 mg kg-1) oxoglaucine improved the outcome of Klebsiella pneumoniae infection, while at higher doses (10 or 20 mg kg-1) the substance caused an impairment of host resistance to infectious agent.
[edit] General Properties
*Molecular Weight
351.35268
*Molecular Formula
C20H17NO5
*IUPAC NAME
N/A
*Canonical Smiles
COC1=C(C2=C3C(=C1)C=CN=C3C(=O)C4=CC(=C(C=C42)OC)OC)OC
*Isomeric Smiles
N/A
*XLogP
2.7
*Topological Polar Surface Area
66.9
