Immunotation of Rv2753c (dihydrodipicolinate synthase)
From DrugPedia: A Wikipedia for Drug discovery
(Difference between revisions)
| Line 1: | Line 1: | ||
| + | {{Drugbox | ||
| + | | IUPAC_name = (8R,9S,10R,13S,14S,17S)- 17-hydroxy-10,13-dimethyl- 1,2,6,7,8,9,11,12,14,15,16,17- dodecahydrocyclopenta[a] phenanthren-3-one | ||
| + | |image=Testosterone structure.png | ||
| + | | width=250 | ||
| + | |image2=Testosterone-balls.png | ||
| + | | CAS_number = 58-22-0 | ||
| + | | CAS_supplemental = <br/> 57-85-2 (propionate ester) <!-- Also CAS verified --> | ||
| + | | ATC_suffix = BA03 | ||
| + | | ATC_supplemental = | ||
| + | | PubChem = 6013 | ||
| + | | DrugBank = DB02901 | ||
| + | | ChemSpiderID = 5791 | ||
| + | | chemical_formula = C<sub>19</sub>H<sub>28</sub>O<sub>2</sub> | ||
| + | | molecular_weight = 288.42 | ||
| + | | smiles = C[C@]43CCC(=O)\C=C4\CC [C@@H]1[C@@H]3CC[C@]2(C) [C@@H](O)CC[C@@H]12 | ||
| + | | synonyms = | ||
| + | | density = | ||
| + | | melting_point = 155<sup>0</sup>deg C EXP | ||
| + | | boiling_point = | ||
| + | | solubility = 23.4 mg/L at 25<sup>0</sup>C EXP | ||
| + | | specific_rotation = +110,2° | ||
| + | | sec_combustion = −11080 kJ/mol | ||
| + | | bioavailability = low (due to extensive [[First pass effect|first pass metabolism]]) | ||
| + | | protein_bound = | ||
| + | | metabolism = [[Liver]], [[Testis]] and [[Prostate]] | ||
| + | | elimination_half-life = 2-4 hours | ||
| + | | excretion = [[Urine]] (90%), feces (6%) | ||
| + | | pregnancy_category= X ([[United States|USA]]), [[Teratogen]]ic effects | ||
| + | | dependency_liability = | ||
| + | | routes_of_administration = Intramuscular injection, transdermal (cream, gel, or patch), sub-'Q' pellet | ||
| + | }} | ||
=General= | =General= | ||
=Antigens= | =Antigens= | ||
| Line 12: | Line 43: | ||
=Alergen Protein= | =Alergen Protein= | ||
=Antibacterial= | =Antibacterial= | ||
| + | =Bacterial Toxin= | ||
| + | =External Links= | ||
| + | |||
| + | [[Category:Immunotation]] | ||
Revision as of 09:01, 9 December 2009
| |
| |
| Immunotation of Rv2753c (dihydrodipicolinate synthase)
| |
| Systematic (IUPAC) name | |
| (8R,9S,10R,13S,14S,17S)- 17-hydroxy-10,13-dimethyl- 1,2,6,7,8,9,11,12,14,15,16,17- dodecahydrocyclopenta[a] phenanthren-3-one | |
| Identifiers | |
| CAS number | 57-85-2 (propionate ester) |
| ATC code | ? |
| PubChem | |
| DrugBank | |
| ChemSpider | |
| Chemical data | |
| Formula | C19H28O2 |
| Mol. mass | 288.42 |
| SMILES | & |
| Physical data | |
| Melt. point | 1550deg C EXP °C |
| Solubility in water | 23.4 mg/L at 250C EXP mg/mL |
| Spec. rot | +110,2° |
| SEC Combust | −11080 kJ/mol |
| Pharmacokinetic data | |
| Bioavailability | low (due to extensive first pass metabolism) |
| Metabolism | Liver, Testis and Prostate |
| Half life | 2-4 hours |
| Excretion | Urine (90%), feces (6%) |
| Therapeutic considerations | |
| Pregnancy cat. |
X (USA), Teratogenic effects |
| Legal status | |
| Routes | Intramuscular injection, transdermal (cream, gel, or patch), sub-'Q' pellet |
Contents |
