PolysacDB Lipopolysaccharide 1392
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Salmonella minnesota R595
[edit] Basic Structure
LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The core oligosaccharide part consists of the following residues : α-Kdop-(2-8)-α-Kdop-(2-->4)-Kdo
[edit] Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
[edit] Antigenic Nature used to produce antibodies
acid-treated and lipid A-coated S. minnesota R597
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab 1F2
[edit] Antibody type and class
IgG1
[edit] Assay System
ELISA, immunoblotting and RIA
[edit] Cross-reactivity
This antibody cross-reacted with E. coli J5, , S. minnesota R595, but did not cross-react with Staphylococcus aureus, E. Coli O111:B4, K. pneumoniae, S. marcescens and P. Aeruginosa and Staphylococcus faecalis
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
N/A
