Gajendra Pal Singh Raghava

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Dr. G. P. S. Raghava Birth_place Uttar Pradesh, India Residence India Nationality Indian Field Bioinformatics Work_Institution Institute of Microbial Technology Bioinformatics Center Religion Hindu
Dr. G. P. S. Raghava Birth_place Uttar Pradesh, India
Residence India Nationality Indian Field Bioinformatics Work_Institution Institute of Microbial Technology Bioinformatics Center Religion Hindu

Gajendra Pal Singh Raghava is a scientist and head of Bioinformatics center, Institute of Microbial Technology (IMTECH), Chandigarh, India (For detail visit his Home Page).

Contents

[edit] Personal

[edit] Early years and Education

Raghava was born in village Nagla Karan, Buland Shahr (UP), India in 1963. He did his B.Sc./M.Sc. from N.A.S. College, Meerut, UP in 1982. His major subjects were Physics, Chemistry and Mathematics. He did his M.Sc in Physics with specialization in electronics from N.A.S. College, Meerut, UP in 1984. He did his M.Tech from Indian Institute of Technology (I.I.T.), New Delhi in 1986. In 1996 he received his Doctorate degree from Institute of Microbial Technology and Panjab University, Chandigarh in area of Bioinformatics. His PhD work focuses on "Computer Aided Prediction of Protein Conformation from Amino Acid Sequences of Biotechnological Relevance".

[edit] Career and Higher Studies

He joined Institute of Microbial Technology, Chandigarh in 1986 as computer scientist. His primary duty was to develop/maintain computer software/hardware and IT infrastructure. He become head of bioinformatics center in 1994. He is also coordinator of distributed information centre (DIC) supported by DBT under BTISNET programme, where his primary duty is to built/maintain infrastructure required for protein modeling and engineering.

He worked as a Post Doctorate Fellow (PDF) at Oxford university as well as at European Bioinformatics Institute (EBI) Cambridge, United Kingdom for two years (1996–98). During this period he learned and developed number of web servers in area of computational biology particularly in Protein Modelling.

[edit] Achievements and Awards

Image:Raghava award.png
Dr G P S Raghava receiving India Research Front Award 2009
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Dr G P S Raghava receiving S. S. Bhatnagar Award from Prime Minister Dr Manmohan Singh
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Dr G P S Raghava receiving National Bioscience Award from Science and Technology minister Shri Kapil Sibal

[edit] Distinguished Positions

[edit] Research interests

Accidentally in 1991, he got interest in research and developed a method for calculating concentration of Antibody/Antigen from ELISA data. In initial phase he developed computer programs for general biological problems. In later stage he developed prediction method for protein secondary structure prediction; his methods successfully compete in international competitions like casp. In 1999 he establish his research group at IMTECH with emphasis on proteins structure prediction and genome annotation. In 2001, his group also focussed on "Computer aided vaccine design" with emphasis on subunit vaccine design. Since 2006, his group is trying to integrate bioinformatics, chemoinformatics, pharmacoinformatics, clinical informatics in order to develop single plate form for designing drugs in insilico.

[edit] Web Services and Software

He believes in public domain software or open source software/documents. Thus his group is using free software and building infrastructure for bioinformatics. All software and web servers developed at his group are free for academic use. Recently his group have initiated a web portal Computational Resource for Drug Discovery (CRDD) under Open Source Drug Discovery . Services provided from his group can be broadly classified in following categories.

[edit] Computer-aided Protein Structure Prediction

Table I Computer-aided Protein Structure Prediction software
APSSP2 PROCLASS PSA RPFOLDBTEVALBetatPred2BetatPredCHpredictAR_NHPred
TBBPredBetaTurnsBhairPredOXBenchStruCompGammaPredAlphaPredPepStrSarPred

[edit] Immunoinformatics: Subunit Vaccine design

Table II Immunoinformatics software
PROPRED1nHLApredMMBpredPcleavageTAPpredCTLpredPROPRED
HLADR4predMHC2predMHCMHCbenchAbAgBCEpredABCpred
BCIPepHLApredMHCBNHaptenDBHLA_affiFDR4Tmhcpred
CBtope NPtope

[edit] Genome Annotation

Table III Genome Annotation software
FTGGWBLASTGWFASTAEGPredSVMgene
SRFMyPatternGeneBenchFTGPredCDpred
DNAbinderPolyapredPprintECGpredSGpred
PHDcleav siRNApred DesiRm MARSpred Iccaars

[edit] Functional Annotation of Proteins

Table IV Functional Annotation software
AC2DgelNRpredGPCRpredGPCRsclassESLpredPSLpredBTXpredMitpred ESLpred2
SRTpredOxypredVGIchanHSLpredDNAsizeGSTpredMangoLGEpred CytoPred
NTXpredVICMpredAlgPredPseaPredRSL-PredAntiBPCOPidsiRNAPred ISSPred
SubMitPred CyclinPred ChemoPred TBPred ProPrint plPred PseaPred2 ChloroPred SPred
PFMPred CancerPred

[edit] Chemoinformatics and Pharmacoinformatics

Table V Chemoinformatics and Pharmacoinformatics software
DADPREDDMKPredKiDoQ AntiBP AntiBP2 TOXIpred

[edit] Unclassified webservers and webpages

Table VI
Crag CRIP HIVbio BioTherapy GDPbio DrugPedia
LibNet Address RBpred Hplot Mafft SFEpred
OC Web Protanal Strucomp Sci. Writ Aasim BioSuite

[edit] Databases

List of Databases developed
MHCBNBCIPEPHaptenDBFSGPPRRDBHMRbase
AntigenDB PolysacDB OXDBase BIAdb SFdbase HIVsir

[edit] News from Group

Paper published

Pawar, B. and Raghava, G.P.S (2010) Prediction and classification of aminoacyl tRNA synthetases using PROSITE domains. BMC Genomics 2010, 11:507

[edit] External links

Template:SSBPST recipients in Biological Science